FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2024643977> ?p ?o ?g. }

• W2024643977 endingPage "81" @default.
• W2024643977 startingPage "69" @default.
• W2024643977 abstract "Purpose Glioblastoma Multiforme (GBM) is the most common and lethal primary brain tumor in adults. The goal of this study was to test the predictive value of MR parameters in relation to the survival of patients with newly diagnosed GBM who were scanned prior to receiving adjuvant radiation and chemotherapy. Methods The study population comprised 68 patients who had surgical resection and were to be treated with fractionated external beam radiation therapy and chemotherapy. Imaging scans included anatomical MRI, diffusion and perfusion weighted imaging and 1H MRSI. The MR data were acquired 3–5 weeks after surgery and approximately 1 week before treatment with radiation therapy. The diffusion, perfusion and spectroscopic parameter values were quantified and subjected to proportional hazards analysis that was adjusted for age and scanner field strength. Results The patients with larger lesion burden based upon volumes of anatomic lesions, volume of CNI2 (number of voxels within the T2 lesion having choline to NAA index >2), volume of CBV3 (number of pixels within the T2 lesion having relative cerebral blood volume >3), and volume of nADC1.5 (number of pixels within the T2 lesion having normalized apparent diffusion coefficient <1.5) had a higher risk for poor outcome. High intensities of combined measures of lactate and lipid in the T2 and CNI2 regions were also associated with poor survival. Conclusions Our study indicated that several pre-treatment anatomic, physiological and metabolic MR parameters are predictive of survival. This information may be important for stratifying patients to specific treatment protocols and for planning focal therapy." @default.
• W2024643977 created "2016-06-24" @default.
• W2024643977 creator A5002900897 @default.
• W2024643977 creator A5031916033 @default.
• W2024643977 creator A5046465813 @default.
• W2024643977 creator A5051168746 @default.
• W2024643977 creator A5061018141 @default.
• W2024643977 creator A5080170176 @default.
• W2024643977 creator A5081059312 @default.
• W2024643977 date "2008-09-23" @default.
• W2024643977 modified "2023-10-16" @default.
• W2024643977 title "Evaluation of MR markers that predict survival in patients with newly diagnosed GBM prior to adjuvant therapy" @default.
• W2024643977 cites W1508981216 @default.
• W2024643977 cites W1897881764 @default.
• W2024643977 cites W1908800763 @default.
• W2024643977 cites W1967269572 @default.
• W2024643977 cites W1977208626 @default.
• W2024643977 cites W1979227464 @default.
• W2024643977 cites W1990556342 @default.
• W2024643977 cites W1995577320 @default.
• W2024643977 cites W1995727099 @default.
• W2024643977 cites W2001744724 @default.
• W2024643977 cites W2005558571 @default.
• W2024643977 cites W2006654035 @default.
• W2024643977 cites W2012514923 @default.
• W2024643977 cites W2012939329 @default.
• W2024643977 cites W2019830967 @default.
• W2024643977 cites W2030331570 @default.
• W2024643977 cites W2032797370 @default.
• W2024643977 cites W2037649963 @default.
• W2024643977 cites W2038931331 @default.
• W2024643977 cites W2049159023 @default.
• W2024643977 cites W2052320391 @default.
• W2024643977 cites W2056446086 @default.
• W2024643977 cites W2057555825 @default.
• W2024643977 cites W2061554178 @default.
• W2024643977 cites W2064214863 @default.
• W2024643977 cites W2065438335 @default.
• W2024643977 cites W2069699241 @default.
• W2024643977 cites W2071752743 @default.
• W2024643977 cites W2082793256 @default.
• W2024643977 cites W2083111640 @default.
• W2024643977 cites W2088411836 @default.
• W2024643977 cites W2088525173 @default.
• W2024643977 cites W2088970226 @default.
• W2024643977 cites W2090298833 @default.
• W2024643977 cites W2092721488 @default.
• W2024643977 cites W2105409367 @default.
• W2024643977 cites W2108024566 @default.
• W2024643977 cites W2112522939 @default.
• W2024643977 cites W2115964253 @default.
• W2024643977 cites W2127988996 @default.
• W2024643977 cites W2128770137 @default.
• W2024643977 cites W2129816075 @default.
• W2024643977 cites W2130950654 @default.
• W2024643977 cites W2134637191 @default.
• W2024643977 cites W2139158372 @default.
• W2024643977 cites W2147746609 @default.
• W2024643977 cites W2152121803 @default.
• W2024643977 cites W2155165718 @default.
• W2024643977 cites W2157101750 @default.
• W2024643977 cites W2168083503 @default.
• W2024643977 cites W2169537399 @default.
• W2024643977 cites W2169590480 @default.
• W2024643977 cites W2400489288 @default.
• W2024643977 cites W301227854 @default.
• W2024643977 cites W4293241248 @default.
• W2024643977 doi "https://doi.org/10.1007/s11060-008-9685-3" @default.
• W2024643977 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3022437" @default.
• W2024643977 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18810326" @default.
• W2024643977 hasPublicationYear "2008" @default.
• W2024643977 type Work @default.
• W2024643977 sameAs 2024643977 @default.
• W2024643977 citedByCount "133" @default.
• W2024643977 countsByYear W20246439772012 @default.
• W2024643977 countsByYear W20246439772013 @default.
• W2024643977 countsByYear W20246439772014 @default.
• W2024643977 countsByYear W20246439772015 @default.
• W2024643977 countsByYear W20246439772016 @default.
• W2024643977 countsByYear W20246439772017 @default.
• W2024643977 countsByYear W20246439772018 @default.
• W2024643977 countsByYear W20246439772019 @default.
• W2024643977 countsByYear W20246439772020 @default.
• W2024643977 countsByYear W20246439772021 @default.
• W2024643977 countsByYear W20246439772022 @default.
• W2024643977 countsByYear W20246439772023 @default.
• W2024643977 crossrefType "journal-article" @default.
• W2024643977 hasAuthorship W2024643977A5002900897 @default.
• W2024643977 hasAuthorship W2024643977A5031916033 @default.
• W2024643977 hasAuthorship W2024643977A5046465813 @default.
• W2024643977 hasAuthorship W2024643977A5051168746 @default.
• W2024643977 hasAuthorship W2024643977A5061018141 @default.
• W2024643977 hasAuthorship W2024643977A5080170176 @default.
• W2024643977 hasAuthorship W2024643977A5081059312 @default.
• W2024643977 hasBestOaLocation W20246439772 @default.
• W2024643977 hasConcept C126322002 @default.
• W2024643977 hasConcept C126838900 @default.
• W2024643977 hasConcept C142724271 @default.

• next