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- W2024652862 abstract "To evaluate the anatomical and functional effect of intravitreous aflibercept (IAI) for the treatment of polypoidal choroidal vasculopathy (PCV) associated with exudative AMD, with a follow up of 3 months.This is a case series study that included 22 eyes with active PCV. All eyes were naive to treatment before inclusion in the study. The treatment protocol consisted of an induction phase of 3 IAI, then the injections were done every 2 months. A complete ophthalmologic workup was done for every patient and included: best corrected visual acuity (ETDRS scale), Fluorescein and Indocyanine Green Angiography, EDI-OCT (Spectralis HRA+OCT®, Heidelberg engineering). All results were analyzed at inclusion and at 3 months.The mean age was 76.3 +/- 11.3. Male to female ratio was 1. The BCVA improved at 3 months (0.58 +/- 0.39logMAR vs 0.20±0.27 log MAR; p= 0.01). The patients gained a mean of 15 letters in the BCVA. No loss of BCVA was noted in any patient. The central macular thickness improved significantly from 376.77+/-99.54 to 279.80±82.53 at 3 months (p= 0.043).The polyp’s regression started at one month after the first injection and was almost complete at 3 months. A significant improvement of retinal pigment epithelium detachment" @default.
- W2024652862 created "2016-06-24" @default.
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- W2024652862 date "2014-08-20" @default.
- W2024652862 modified "2023-09-23" @default.
- W2024652862 title "Therapeutic approaches- aflibercept first french results of intravitreous aflibercept for active naïve polypoidal choroidal vasculopathy-6 months follow up" @default.
- W2024652862 doi "https://doi.org/10.1111/j.1755-3768.2014.2414.x" @default.
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