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- W2024657512 abstract "The stimulation of calcium efflux from Swiss 3T6 mouse fibroblasts by extracellular ATP was studied. It was found that the cells could be desensitized to ATP by a previous exposure to the nucleotide, lending support to the theory that this is a receptor mediated process. Another ATP-receptor mediated process in Swiss 3T6 cells, that is also subject to desensitization, causes the permeabilization of the plasma membrane to nucleotides and other normally impermeant compounds [Gonzalez et al., J. Cell. Physiol. 139:109 (1989)]. Here we demonstrate that selective desensitization of the ATP-dependent calcium mobilization pathway can be achieved without affecting ATP-induced permeabilization. Data are presented in support of the existence of multiple ATP-receptors (purinoceptors) in Swiss 3T6 cells." @default.
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- W2024657512 date "1989-10-01" @default.
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- W2024657512 title "Two distinct receptors for ATP can be distinguished in Swiss 3T6 mouse fibroblasts by their desensitization" @default.
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- W2024657512 doi "https://doi.org/10.1016/0006-291x(89)91517-9" @default.
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