Matches in SemOpenAlex for { <https://semopenalex.org/work/W2024659898> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W2024659898 abstract "We are studying the effectiveness of a semicircular canal prosthesis to improve postural control, perception of spatial orientation, and the VOR in rhesus monkeys with bilateral vestibular hypofunction. Balance is examined by measuring spontaneous sway of the body during quiet stance and postural responses evoked by head turns and rotation of the support surface; perception is measured with a task derived from the subjective visual vertical (SVV) test during static and dynamic rotation in the roll plane; and the angular VOR is measured during rotation about the roll, pitch, and yaw axes. After the normal responses are characterized, bilateral vestibular loss is induced with intratympanic gentamicin, and then multisite stimulating electrodes are chronically implanted into the ampullae of all three canals in one ear. The postural, perceptual, and VOR responses are then characterized in the ablated state, and then bilateral, chronic electrical stimulation is applied to the ampullary nerves using a prosthesis that senses angular head velocity in three-dimensions and uses this information to modulate the rate of current pulses provided by the implanted electrodes. We are currently characterizing two normal monkeys with these paradigms, and vestibular ablation and electrode implantation are planned for the near future. In one prior rhesus monkey tested with this approach, we found that a one-dimensional (posterior canal) prosthesis improved balance during head turns, perceived head orientation during roll tilts, and the VOR in the plane of the instrumented canal. We therefore predict that the more complete information provided by a three-dimensional prosthesis that modulates activity in bilaterally-paired canals will exceed the benefits provided by the one-dimensional, unilateral approach used in our preliminary studies." @default.
- W2024659898 created "2016-06-24" @default.
- W2024659898 creator A5004416210 @default.
- W2024659898 creator A5012472298 @default.
- W2024659898 creator A5015497153 @default.
- W2024659898 creator A5018401229 @default.
- W2024659898 creator A5046928489 @default.
- W2024659898 creator A5069735967 @default.
- W2024659898 creator A5090700133 @default.
- W2024659898 date "2011-08-01" @default.
- W2024659898 modified "2023-09-24" @default.
- W2024659898 title "Vestibular prosthesis tested in rhesus monkeys" @default.
- W2024659898 cites W2066035485 @default.
- W2024659898 cites W2078118095 @default.
- W2024659898 cites W2144887161 @default.
- W2024659898 cites W2145860775 @default.
- W2024659898 cites W2150603260 @default.
- W2024659898 doi "https://doi.org/10.1109/iembs.2011.6090573" @default.
- W2024659898 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3594774" @default.
- W2024659898 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22254795" @default.
- W2024659898 hasPublicationYear "2011" @default.
- W2024659898 type Work @default.
- W2024659898 sameAs 2024659898 @default.
- W2024659898 citedByCount "5" @default.
- W2024659898 countsByYear W20246598982015 @default.
- W2024659898 countsByYear W20246598982020 @default.
- W2024659898 crossrefType "proceedings-article" @default.
- W2024659898 hasAuthorship W2024659898A5004416210 @default.
- W2024659898 hasAuthorship W2024659898A5012472298 @default.
- W2024659898 hasAuthorship W2024659898A5015497153 @default.
- W2024659898 hasAuthorship W2024659898A5018401229 @default.
- W2024659898 hasAuthorship W2024659898A5046928489 @default.
- W2024659898 hasAuthorship W2024659898A5069735967 @default.
- W2024659898 hasAuthorship W2024659898A5090700133 @default.
- W2024659898 hasBestOaLocation W20246598982 @default.
- W2024659898 hasConcept C105702510 @default.
- W2024659898 hasConcept C141071460 @default.
- W2024659898 hasConcept C16345878 @default.
- W2024659898 hasConcept C168031717 @default.
- W2024659898 hasConcept C190041318 @default.
- W2024659898 hasConcept C2524010 @default.
- W2024659898 hasConcept C2777340575 @default.
- W2024659898 hasConcept C2778500370 @default.
- W2024659898 hasConcept C2778715743 @default.
- W2024659898 hasConcept C2779650682 @default.
- W2024659898 hasConcept C31972630 @default.
- W2024659898 hasConcept C33923547 @default.
- W2024659898 hasConcept C41008148 @default.
- W2024659898 hasConcept C548259974 @default.
- W2024659898 hasConcept C71924100 @default.
- W2024659898 hasConcept C74050887 @default.
- W2024659898 hasConcept C99508421 @default.
- W2024659898 hasConceptScore W2024659898C105702510 @default.
- W2024659898 hasConceptScore W2024659898C141071460 @default.
- W2024659898 hasConceptScore W2024659898C16345878 @default.
- W2024659898 hasConceptScore W2024659898C168031717 @default.
- W2024659898 hasConceptScore W2024659898C190041318 @default.
- W2024659898 hasConceptScore W2024659898C2524010 @default.
- W2024659898 hasConceptScore W2024659898C2777340575 @default.
- W2024659898 hasConceptScore W2024659898C2778500370 @default.
- W2024659898 hasConceptScore W2024659898C2778715743 @default.
- W2024659898 hasConceptScore W2024659898C2779650682 @default.
- W2024659898 hasConceptScore W2024659898C31972630 @default.
- W2024659898 hasConceptScore W2024659898C33923547 @default.
- W2024659898 hasConceptScore W2024659898C41008148 @default.
- W2024659898 hasConceptScore W2024659898C548259974 @default.
- W2024659898 hasConceptScore W2024659898C71924100 @default.
- W2024659898 hasConceptScore W2024659898C74050887 @default.
- W2024659898 hasConceptScore W2024659898C99508421 @default.
- W2024659898 hasLocation W20246598981 @default.
- W2024659898 hasLocation W20246598982 @default.
- W2024659898 hasLocation W20246598983 @default.
- W2024659898 hasOpenAccess W2024659898 @default.
- W2024659898 hasPrimaryLocation W20246598981 @default.
- W2024659898 hasRelatedWork W1993588871 @default.
- W2024659898 hasRelatedWork W1995553734 @default.
- W2024659898 hasRelatedWork W2007977755 @default.
- W2024659898 hasRelatedWork W2023979793 @default.
- W2024659898 hasRelatedWork W2063290215 @default.
- W2024659898 hasRelatedWork W2072283644 @default.
- W2024659898 hasRelatedWork W2116013564 @default.
- W2024659898 hasRelatedWork W2206819273 @default.
- W2024659898 hasRelatedWork W2255975054 @default.
- W2024659898 hasRelatedWork W2321495811 @default.
- W2024659898 hasRelatedWork W2402682231 @default.
- W2024659898 hasRelatedWork W2486928131 @default.
- W2024659898 hasRelatedWork W2920329164 @default.
- W2024659898 hasRelatedWork W2968800093 @default.
- W2024659898 hasRelatedWork W2983854607 @default.
- W2024659898 hasRelatedWork W3032516386 @default.
- W2024659898 hasRelatedWork W3174786421 @default.
- W2024659898 hasRelatedWork W79498309 @default.
- W2024659898 hasRelatedWork W84840729 @default.
- W2024659898 hasRelatedWork W2836888774 @default.
- W2024659898 isParatext "false" @default.
- W2024659898 isRetracted "false" @default.
- W2024659898 magId "2024659898" @default.
- W2024659898 workType "article" @default.