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- W2024661675 abstract "The cell cycle oscillator, based on a core negative feedback loop and modified extensively by positive feedback, cycles with a frequency that is regulated by environmental and developmental programs to encompass a wide range of cell cycle times. We discuss how positive feedback allows frequency tuning, how size and morphogenetic checkpoints regulate oscillator frequency, and how extrinsic oscillators such as the circadian clock gate cell cycle frequency. The master cell cycle regulatory oscillator in turn controls the frequency of peripheral oscillators controlling essential events. A recently proposed phase-locking model accounts for this coupling." @default.
- W2024661675 created "2016-06-24" @default.
- W2024661675 creator A5061209953 @default.
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- W2024661675 date "2010-12-01" @default.
- W2024661675 modified "2023-10-18" @default.
- W2024661675 title "Frequency control of cell cycle oscillators" @default.
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- W2024661675 doi "https://doi.org/10.1016/j.gde.2010.08.006" @default.
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