Matches in SemOpenAlex for { <https://semopenalex.org/work/W2024662227> ?p ?o ?g. }
Showing items 1 to 87 of
87
with 100 items per page.
- W2024662227 endingPage "454" @default.
- W2024662227 startingPage "447" @default.
- W2024662227 abstract "The effect of intracerebroventricular (i.c.v.) treatment with a vasopressin (AVP) V1-receptor antagonist on the pressor response to i.c.v. injection of Clonidine was investigated in conscious rats with chronic i.c.v. guide cannulas and an arterial catheter. In conscious rats, i.c.v.-injected Clonidine (5 and 10 μg) dose-dependently produced a pressor response with a decrease in heart rate. No significant depressor response was induced by Clonidine. The i.c.v. pretreatment with an AVP V1-receptor antagonist ([d(CH2)5-Tyr(Me)]-AVP) at 0.5–2.5 μg dose-dependently inhibited the pressor response to 10 μg of i.c.v.-injected Clonidine, while systemic (i.v.) pretreatment with the antagonist (2.5 μg) had no effect. In pentobarbital-anesthetized rats, 10 μg of i.c.v.-injected Clonidine caused a marked depressor response associated with bradycardia. However, i.c.v. pretreatment with the antagonist (2.5 μg) did not affect cardiovascular responses to i.c.v.-injected Clonidine. These results suggest that endogenous AVP in the brain is involved in the mechanisms underlying the pressor response to i.c.v.-injected Clonidine in conscious rats." @default.
- W2024662227 created "2016-06-24" @default.
- W2024662227 creator A5052164179 @default.
- W2024662227 creator A5062359155 @default.
- W2024662227 creator A5074971816 @default.
- W2024662227 date "1993-01-01" @default.
- W2024662227 modified "2023-10-05" @default.
- W2024662227 title "Intracerebroventricular Treatment with Vasopressin V1-Receptor Antagonist Inhibits Centrally-Mediated Pressor Response to Clonidine in Conscious Rats" @default.
- W2024662227 cites W1972389227 @default.
- W2024662227 cites W1974579901 @default.
- W2024662227 cites W1982622069 @default.
- W2024662227 cites W2009431062 @default.
- W2024662227 cites W2010618981 @default.
- W2024662227 cites W2023003742 @default.
- W2024662227 cites W2029098705 @default.
- W2024662227 cites W2034988536 @default.
- W2024662227 cites W2055120398 @default.
- W2024662227 cites W2055350950 @default.
- W2024662227 cites W2063027570 @default.
- W2024662227 cites W2080369046 @default.
- W2024662227 cites W2085655028 @default.
- W2024662227 cites W2085674782 @default.
- W2024662227 cites W2156606373 @default.
- W2024662227 cites W3098349504 @default.
- W2024662227 doi "https://doi.org/10.1254/jjp.63.447" @default.
- W2024662227 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8121079" @default.
- W2024662227 hasPublicationYear "1993" @default.
- W2024662227 type Work @default.
- W2024662227 sameAs 2024662227 @default.
- W2024662227 citedByCount "3" @default.
- W2024662227 countsByYear W20246622272012 @default.
- W2024662227 countsByYear W20246622272023 @default.
- W2024662227 crossrefType "journal-article" @default.
- W2024662227 hasAuthorship W2024662227A5052164179 @default.
- W2024662227 hasAuthorship W2024662227A5062359155 @default.
- W2024662227 hasAuthorship W2024662227A5074971816 @default.
- W2024662227 hasBestOaLocation W20246622271 @default.
- W2024662227 hasConcept C126322002 @default.
- W2024662227 hasConcept C134018914 @default.
- W2024662227 hasConcept C170493617 @default.
- W2024662227 hasConcept C185592680 @default.
- W2024662227 hasConcept C2776370428 @default.
- W2024662227 hasConcept C2776885963 @default.
- W2024662227 hasConcept C2777495988 @default.
- W2024662227 hasConcept C2777953023 @default.
- W2024662227 hasConcept C2778122271 @default.
- W2024662227 hasConcept C2778399450 @default.
- W2024662227 hasConcept C2779881253 @default.
- W2024662227 hasConcept C71924100 @default.
- W2024662227 hasConcept C84393581 @default.
- W2024662227 hasConcept C90474776 @default.
- W2024662227 hasConceptScore W2024662227C126322002 @default.
- W2024662227 hasConceptScore W2024662227C134018914 @default.
- W2024662227 hasConceptScore W2024662227C170493617 @default.
- W2024662227 hasConceptScore W2024662227C185592680 @default.
- W2024662227 hasConceptScore W2024662227C2776370428 @default.
- W2024662227 hasConceptScore W2024662227C2776885963 @default.
- W2024662227 hasConceptScore W2024662227C2777495988 @default.
- W2024662227 hasConceptScore W2024662227C2777953023 @default.
- W2024662227 hasConceptScore W2024662227C2778122271 @default.
- W2024662227 hasConceptScore W2024662227C2778399450 @default.
- W2024662227 hasConceptScore W2024662227C2779881253 @default.
- W2024662227 hasConceptScore W2024662227C71924100 @default.
- W2024662227 hasConceptScore W2024662227C84393581 @default.
- W2024662227 hasConceptScore W2024662227C90474776 @default.
- W2024662227 hasIssue "4" @default.
- W2024662227 hasLocation W20246622271 @default.
- W2024662227 hasLocation W20246622272 @default.
- W2024662227 hasOpenAccess W2024662227 @default.
- W2024662227 hasPrimaryLocation W20246622271 @default.
- W2024662227 hasRelatedWork W1981269750 @default.
- W2024662227 hasRelatedWork W2024662227 @default.
- W2024662227 hasRelatedWork W2035774772 @default.
- W2024662227 hasRelatedWork W2063781338 @default.
- W2024662227 hasRelatedWork W2072936344 @default.
- W2024662227 hasRelatedWork W2079693849 @default.
- W2024662227 hasRelatedWork W2084275810 @default.
- W2024662227 hasRelatedWork W2138491398 @default.
- W2024662227 hasRelatedWork W2278420649 @default.
- W2024662227 hasRelatedWork W2563938602 @default.
- W2024662227 hasVolume "63" @default.
- W2024662227 isParatext "false" @default.
- W2024662227 isRetracted "false" @default.
- W2024662227 magId "2024662227" @default.
- W2024662227 workType "article" @default.