FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2024685809> ?p ?o ?g. }

• W2024685809 endingPage "2703" @default.
• W2024685809 startingPage "2694" @default.
• W2024685809 abstract "Fluorescence recovery after photobleaching (FRAP) is a powerful technique to study molecular dynamics inside living cells. During the past years, several laboratories have used FRAP to image the motion of RNA-protein and other macromolecular complexes in the nucleus and cytoplasm. In the case of mRNAs, there is growing evidence indicating that these molecules assemble into large ribonucleoprotein complexes that diffuse throughout the nucleus by Brownian motion. However, estimates of the corresponding diffusion rate yielded values that differ by up to one order of magnitude. In vivo labeling of RNA relies on indirect tagging with a fluorescent probe, and here we show how the binding affinity of the probe to the target RNA influences the effective diffusion estimates of the resulting complex. We extend current reaction-diffusion models for FRAP by allowing for diffusion of the bound complex. This more general model can be used to fit any fluorescence recovery curve involving two interacting mobile species in the cell (a fluorescent probe and its target substrate). The results show that interpreting FRAP data in light of the new model reconciles the discrepant mRNA diffusion-rate values previously reported." @default.
• W2024685809 created "2016-06-24" @default.
• W2024685809 creator A5015996943 @default.
• W2024685809 creator A5056179411 @default.
• W2024685809 creator A5083230780 @default.
• W2024685809 date "2007-04-01" @default.
• W2024685809 modified "2023-10-05" @default.
• W2024685809 title "A Reaction-Diffusion Model to Study RNA Motion by Quantitative Fluorescence Recovery after Photobleaching" @default.
• W2024685809 cites W146515307 @default.
• W2024685809 cites W1485725607 @default.
• W2024685809 cites W1492285013 @default.
• W2024685809 cites W1570419937 @default.
• W2024685809 cites W1635552303 @default.
• W2024685809 cites W1975210552 @default.
• W2024685809 cites W1977930114 @default.
• W2024685809 cites W1978122953 @default.
• W2024685809 cites W1983099693 @default.
• W2024685809 cites W1993434836 @default.
• W2024685809 cites W1995553090 @default.
• W2024685809 cites W1996419188 @default.
• W2024685809 cites W2009071546 @default.
• W2024685809 cites W2013804512 @default.
• W2024685809 cites W2015884353 @default.
• W2024685809 cites W2017305207 @default.
• W2024685809 cites W2017934591 @default.
• W2024685809 cites W2025183885 @default.
• W2024685809 cites W2052606706 @default.
• W2024685809 cites W2058041522 @default.
• W2024685809 cites W2059929101 @default.
• W2024685809 cites W2068185463 @default.
• W2024685809 cites W2081143003 @default.
• W2024685809 cites W2083773088 @default.
• W2024685809 cites W2089191944 @default.
• W2024685809 cites W2096594220 @default.
• W2024685809 cites W2097627784 @default.
• W2024685809 cites W2101353820 @default.
• W2024685809 cites W2116131625 @default.
• W2024685809 cites W2118789825 @default.
• W2024685809 cites W2121252755 @default.
• W2024685809 cites W2126149754 @default.
• W2024685809 cites W2128942354 @default.
• W2024685809 cites W2136180087 @default.
• W2024685809 cites W2147195316 @default.
• W2024685809 cites W2148326399 @default.
• W2024685809 cites W2155992634 @default.
• W2024685809 cites W2157031202 @default.
• W2024685809 cites W2163400869 @default.
• W2024685809 cites W2164285177 @default.
• W2024685809 cites W2172169009 @default.
• W2024685809 cites W85002878 @default.
• W2024685809 doi "https://doi.org/10.1529/biophysj.106.096693" @default.
• W2024685809 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1831683" @default.
• W2024685809 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17259280" @default.
• W2024685809 hasPublicationYear "2007" @default.
• W2024685809 type Work @default.
• W2024685809 sameAs 2024685809 @default.
• W2024685809 citedByCount "74" @default.
• W2024685809 countsByYear W20246858092012 @default.
• W2024685809 countsByYear W20246858092013 @default.
• W2024685809 countsByYear W20246858092014 @default.
• W2024685809 countsByYear W20246858092015 @default.
• W2024685809 countsByYear W20246858092017 @default.
• W2024685809 countsByYear W20246858092018 @default.
• W2024685809 countsByYear W20246858092019 @default.
• W2024685809 countsByYear W20246858092020 @default.
• W2024685809 countsByYear W20246858092021 @default.
• W2024685809 countsByYear W20246858092022 @default.
• W2024685809 countsByYear W20246858092023 @default.
• W2024685809 crossrefType "journal-article" @default.
• W2024685809 hasAuthorship W2024685809A5015996943 @default.
• W2024685809 hasAuthorship W2024685809A5056179411 @default.
• W2024685809 hasAuthorship W2024685809A5083230780 @default.
• W2024685809 hasBestOaLocation W20246858091 @default.
• W2024685809 hasConcept C104317684 @default.
• W2024685809 hasConcept C112401455 @default.
• W2024685809 hasConcept C120665830 @default.
• W2024685809 hasConcept C121332964 @default.
• W2024685809 hasConcept C12554922 @default.
• W2024685809 hasConcept C144618238 @default.
• W2024685809 hasConcept C185592680 @default.
• W2024685809 hasConcept C190062978 @default.
• W2024685809 hasConcept C26659971 @default.
• W2024685809 hasConcept C2780723820 @default.
• W2024685809 hasConcept C31332276 @default.
• W2024685809 hasConcept C55493867 @default.
• W2024685809 hasConcept C62520636 @default.
• W2024685809 hasConcept C67705224 @default.
• W2024685809 hasConcept C69357855 @default.
• W2024685809 hasConcept C86803240 @default.
• W2024685809 hasConcept C91881484 @default.
• W2024685809 hasConcept C95444343 @default.
• W2024685809 hasConcept C97355855 @default.
• W2024685809 hasConceptScore W2024685809C104317684 @default.
• W2024685809 hasConceptScore W2024685809C112401455 @default.
• W2024685809 hasConceptScore W2024685809C120665830 @default.
• W2024685809 hasConceptScore W2024685809C121332964 @default.
• W2024685809 hasConceptScore W2024685809C12554922 @default.
• W2024685809 hasConceptScore W2024685809C144618238 @default.

• next