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- W2024697012 abstract "Multifactorial heredity, involving interaction between genetic and environmental factors, is the model hypothesized for psoriasis causation. Measures of heritability indicate that from 50 % to 90 % of the psoriatic phenotype is connected with genetic factors. The remaining variability is due to environmental factors. Candidate risk factors can be initially identified by analyzing variations in population incidence or prevalence. A trend toward increasing incidence of psoriasis in recent decades has been documented. Analytic epidemiologic studies offer a better insight into risk factors allowing to obtain quantitative estimates of the contribution of a factor of interest to the disease and to control for potential confounders. Smoking habits, alcohol consumption, diet, obesity, physical inactivity, infection, drugs, and stressful life events have been considered as candidate risk factors. Convincing proofs exist for only a few of them, namely smoking and obesity. Knowledge of potentially avoidable risk factors may offer clues to plan preventive measures." @default.
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- W2024697012 date "2013-01-11" @default.
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- W2024697012 title "Risk Factors for Psoriasis" @default.
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