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• W2024698509 abstract "S ummary . Indications for treatment of aplastic anaemia (AA) by marrow transplantation are discussed. Selection of donor‐recipient pairs by histocompatibility testing, conditioning of patients for transplantation, technique of grafting, post‐grafting care and immunosuppressive drug regimens are reviewed. Data are presented on 28 patients with advanced AA treated by marrow grafts from HL‐A matched siblings following conditioning with cyclophosphamide (50 mg/kg) on each of 4 successive days. Survival and haematological reconstitution in more than half the patients indicates that marrow grafting in patients with advanced AA should be undertaken early, before major infections and refractoriness to blood transfusions occur provided that an HL‐A matched sibling can be identified as a donor. The results have shown that survival in marrow grafted patients with severe AA compares favourably to that of patients treated with conventional therapy." @default.
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• W2024698509 date "1975-08-01" @default.
• W2024698509 modified "2023-10-16" @default.
• W2024698509 title "Bone Marrow Transplantation for Aplastic Anaemia" @default.
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• W2024698509 doi "https://doi.org/10.1111/j.1365-2141.1975.tb00901.x" @default.
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