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- W2024728970 abstract "Behavioral prevention clinical trials against cognitive decline could play an important role in reducing incidence of dementia. However, those who volunteer to participate in this type of trial could be high-functioning individuals with very active life styles. This reduces the generalizability of trial results. We conducted a randomized clinical trial where increasing social interactions using computers and webcams could result in improved cognitive functions. Before the trial, we examined characteristics associated with willingness to participate in the trial by distributing surveys in the community as a part of recruitment strategies. 2000 surveys were distributed to retirement communities located in the metropolitan Portland, OR. After a paragraph briefly introducing our behavioral clinical trial, we asked (1) whether the subject is interested in participating in the trial (yes/no), and (2) to provide their contact information (name, address and phone number) if they would like to participate in the trial. Subjects were informed that they could decline to participate any time after hearing about the study. A logistic regression model was run with an outcome indicating those who were interested in the study and provided their contact information. The characteristics associated with likelihood of participating in the trial were examined including basic demographic information, loneliness scale scores, physical activity index, social/cognitive activity index, social network scale, self-rated health, and computer usage. Out of 1020 surveys returned (51% response rate), 586 surveys (57%) had complete data for all the variables of interest. Among these, 223 showed interest in the study and of those, 185 also provided contact information. These 185 subjects were more likely to be higher in social/cognitive activity index (OR= 1.03, p= 0.016),physical activity index (OR= 1.0 5, p<0.001) and current computer user (OR= 3.07, p =0.021), compared with those who answered no to both questions. In a behavioral clinical trial which encourages social interactions using modern technologies, those who agreed to participate were more likely to be socially and physically active and be computer users, with the latter in particular showing a strong association. Increasing familiarity with PC and Internet in the community should improve the generalizability of future trials of this type." @default.
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- W2024728970 date "2013-07-01" @default.
- W2024728970 modified "2023-09-28" @default.
- W2024728970 title "P2-320: Characteristics associated with willingness to participate in technology-based behavioral clinical trials" @default.
- W2024728970 doi "https://doi.org/10.1016/j.jalz.2013.05.968" @default.
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