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• W2024756026 abstract "The effects of the inhibition of steroidogenesis by trilostane on oocyte maturation were examined by studying spontaneous maturation and fertilization in vitro. 10(-6)M trilostane had no influence on the meiotic process, whether the oocytes were naked or not. At a concentration of 10(-6)M and 10(-7)M trilostane, low normal pronuclear formation and high polyspermy were found during in vitro fertilization. However, no retarded male pronuclear development could be detected in the trilostane-treated group. Thus, steroid producing activity within ova is apparently necessary to prevent multiple sperm penetration, but it has no effect on meiosis or the action of the so-called male pronucleus growth factor (MPGF)." @default.
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• W2024756026 date "1984-11-01" @default.
• W2024756026 modified "2023-09-26" @default.
• W2024756026 title "Biological effects of trilostane in vitro on oocyte maturation and fertilization in the hamster" @default.
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• W2024756026 doi "https://doi.org/10.1007/bf01946649" @default.
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