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- W2024763570 abstract "The objective of thisstudy was to examine whether stimulants impact pubertal development inadolescent Attention Deficit Hyperactivity Disorder (ADHD), an understudiedsubject. Pubertal staging data were collected during a 2-year open study ofextended release methylphenidate in adolescents (N = 111)with ADHD. Tanner stages were compared to national estimates. The sample wasprimarily male, Caucasian, and a mean age of 14.8 years at baseline. Thebaseline Tanner stage for 70% of subjects was consistent with chronologicalage. For the majority of subjects who reached 12 - 20months (N = 25) or 24 months (N = 21)endpoints, the Tanner stage at respective endpoints was consistent with age. Wefound that progression in Tannerstage was not associated with OROS MPH duration or dose (p > 0.10).Long-term treatment with extended release methylphenidate did not appear toadversely impact pubertal development in this sample of adolescents with ADHD." @default.
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- W2024763570 date "2014-01-01" @default.
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- W2024763570 title "Impact of Long-Term Treatment with OROS Methylphenidate on Pubertal Development in Adolescents with ADHD" @default.
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- W2024763570 doi "https://doi.org/10.4236/ojpsych.2014.42019" @default.
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