FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2024765633> ?p ?o ?g. }

• W2024765633 endingPage "122" @default.
• W2024765633 startingPage "115" @default.
• W2024765633 abstract "Some types of proteins are intermolecularly cross-linked via the formation of Tyr–Tyr (dityrosine) bonds on illumination in the presence of certain kinds of photosensitizers. The study of reactions of this type is of importance since they appear to be involved in several processes of biomedical importance such as the photosensitized (photodynamic) treatment of tumors, pathological effects of sunlight (skin photoaging, induction of cataracts), etc. The mechanisms involved in the photosensitized formation of dityrosine cross-links are not clear, and the chemical nature of the cross-link(s) is not known. In the present work, these problems have been studied using N-acetyltyrosine as a model substrate. This compound was illuminated under aerobic conditions at pH 6.0 with FMN as the photosensitizer. The Tyr–Tyr cross-linked products were isolated and purified by a preparative silica gel 60 column and by preparative reverse phase HPLC. Three main cross-linked products, designated as 1 (C6, C6′-linked di-(N-acetyltyrosine)), 2 (C6, O7′-linked di-(N-acetyltyrosine)), and 3 (C6, C4′-linked di-(N-acetyltyrosine)), were identified, and their chemical structures were determined by MS, two-dimensional NMR spectral methods, and other standard techniques. Detailed reaction pathways for the formation of the carbon–carbon (1 and 3) and carbon–oxygen (2) coupled products were proposed." @default.
• W2024765633 created "2016-06-24" @default.
• W2024765633 creator A5007440695 @default.
• W2024765633 creator A5062839834 @default.
• W2024765633 creator A5067408418 @default.
• W2024765633 creator A5070774591 @default.
• W2024765633 date "2000-05-01" @default.
• W2024765633 modified "2023-10-03" @default.
• W2024765633 title "Photodynamic cross-linking of proteins" @default.
• W2024765633 cites W1457292348 @default.
• W2024765633 cites W1523652295 @default.
• W2024765633 cites W1973579484 @default.
• W2024765633 cites W1979852924 @default.
• W2024765633 cites W1988871512 @default.
• W2024765633 cites W1989254963 @default.
• W2024765633 cites W2001821608 @default.
• W2024765633 cites W2002534688 @default.
• W2024765633 cites W2009828713 @default.
• W2024765633 cites W2013160253 @default.
• W2024765633 cites W2023209634 @default.
• W2024765633 cites W2027196389 @default.
• W2024765633 cites W2047414357 @default.
• W2024765633 cites W2048111277 @default.
• W2024765633 cites W2050412382 @default.
• W2024765633 cites W2059092348 @default.
• W2024765633 cites W2073401702 @default.
• W2024765633 cites W2076783130 @default.
• W2024765633 cites W2083679702 @default.
• W2024765633 cites W2089243368 @default.
• W2024765633 cites W2089810625 @default.
• W2024765633 cites W2091210609 @default.
• W2024765633 cites W2155644024 @default.
• W2024765633 cites W2168888997 @default.
• W2024765633 cites W2190508491 @default.
• W2024765633 cites W2322016311 @default.
• W2024765633 cites W4251719113 @default.
• W2024765633 doi "https://doi.org/10.1016/s1010-6030(00)00228-8" @default.
• W2024765633 hasPublicationYear "2000" @default.
• W2024765633 type Work @default.
• W2024765633 sameAs 2024765633 @default.
• W2024765633 citedByCount "42" @default.
• W2024765633 countsByYear W20247656332012 @default.
• W2024765633 countsByYear W20247656332013 @default.
• W2024765633 countsByYear W20247656332015 @default.
• W2024765633 countsByYear W20247656332016 @default.
• W2024765633 countsByYear W20247656332017 @default.
• W2024765633 countsByYear W20247656332018 @default.
• W2024765633 countsByYear W20247656332019 @default.
• W2024765633 countsByYear W20247656332020 @default.
• W2024765633 countsByYear W20247656332021 @default.
• W2024765633 crossrefType "journal-article" @default.
• W2024765633 hasAuthorship W2024765633A5007440695 @default.
• W2024765633 hasAuthorship W2024765633A5062839834 @default.
• W2024765633 hasAuthorship W2024765633A5067408418 @default.
• W2024765633 hasAuthorship W2024765633A5070774591 @default.
• W2024765633 hasConcept C111368507 @default.
• W2024765633 hasConcept C127313418 @default.
• W2024765633 hasConcept C178790620 @default.
• W2024765633 hasConcept C185592680 @default.
• W2024765633 hasConcept C21951064 @default.
• W2024765633 hasConcept C2777289219 @default.
• W2024765633 hasConcept C2779532046 @default.
• W2024765633 hasConcept C2781323092 @default.
• W2024765633 hasConcept C2781469039 @default.
• W2024765633 hasConcept C43617362 @default.
• W2024765633 hasConcept C55493867 @default.
• W2024765633 hasConcept C71240020 @default.
• W2024765633 hasConcept C7263354 @default.
• W2024765633 hasConcept C75473681 @default.
• W2024765633 hasConceptScore W2024765633C111368507 @default.
• W2024765633 hasConceptScore W2024765633C127313418 @default.
• W2024765633 hasConceptScore W2024765633C178790620 @default.
• W2024765633 hasConceptScore W2024765633C185592680 @default.
• W2024765633 hasConceptScore W2024765633C21951064 @default.
• W2024765633 hasConceptScore W2024765633C2777289219 @default.
• W2024765633 hasConceptScore W2024765633C2779532046 @default.
• W2024765633 hasConceptScore W2024765633C2781323092 @default.
• W2024765633 hasConceptScore W2024765633C2781469039 @default.
• W2024765633 hasConceptScore W2024765633C43617362 @default.
• W2024765633 hasConceptScore W2024765633C55493867 @default.
• W2024765633 hasConceptScore W2024765633C71240020 @default.
• W2024765633 hasConceptScore W2024765633C7263354 @default.
• W2024765633 hasConceptScore W2024765633C75473681 @default.
• W2024765633 hasIssue "1-2" @default.
• W2024765633 hasLocation W20247656331 @default.
• W2024765633 hasOpenAccess W2024765633 @default.
• W2024765633 hasPrimaryLocation W20247656331 @default.
• W2024765633 hasRelatedWork W1996569391 @default.
• W2024765633 hasRelatedWork W2068003714 @default.
• W2024765633 hasRelatedWork W2127377584 @default.
• W2024765633 hasRelatedWork W2549453171 @default.
• W2024765633 hasRelatedWork W2963416893 @default.
• W2024765633 hasRelatedWork W3002932652 @default.
• W2024765633 hasRelatedWork W3127329048 @default.
• W2024765633 hasRelatedWork W3128824594 @default.
• W2024765633 hasRelatedWork W4281932131 @default.
• W2024765633 hasRelatedWork W4306804977 @default.
• W2024765633 hasVolume "133" @default.

• next