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- W2024768042 abstract "The pressor effects of fat and salt were examined in male Sprague-Dawley rats. Rats fed high carbohydrate (5% corn oil), high salt (8% NaCl) diets demonstrated significant elevations in blood pressure within one week of diet introduction which persisted throughout the 9 week experimental period. High saturated fat (5% corn oil-15% coconut oil) diets promoted a significant elevation in blood pressure, irrespective of the level of dietary salt. High dietary salt, as opposed to basal levels, tended to decrease the blood pressure of rats fed a diet containing all unsaturated fat (20% corn oil). The greatest percent increase in the renal vasodilator prostaglandin E2 was measured in rats fed the high unsaturated-basal salt diet compared to all other dietary treatments. A hypervolemic effect of high levels of dietary salt was demonstrated in the high carbohydrate, all unsaturated fat and high saturated fat groups. These results demonstrate that the amount and type of dietary fat interact with the level of dietary salt to influence blood pressure in rats." @default.
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- W2024768042 date "1981-01-01" @default.
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- W2024768042 title "The effect of dietary fat and salt on blood pressure, renal and aortic prostaglandins" @default.
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- W2024768042 doi "https://doi.org/10.1016/s0271-5317(81)80028-0" @default.
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