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- W2024796881 abstract "From an extract of the Okinawan sponge Petrosia strongylata, five novel acetylenic metabolites, petrosiols A (1)–E (5), were isolated and chemically characterized. These compounds induced nerve growth factor (NGF)-like neuronal differentiation of PC12 cells. The structure–activity relationships of the petrosiols, their derivatives, and some related known compounds suggest the importance of the rare 2,4-diyne-1,6,7,8-tetraol fragment for the neurotrophic activity of the petrosiols." @default.
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- W2024796881 date "2013-01-01" @default.
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- W2024796881 title "Petrosiols A–E, neurotrophic diyne tetraols isolated from the Okinawan sponge Petrosia strongylata" @default.
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- W2024796881 doi "https://doi.org/10.1016/j.tet.2012.10.063" @default.
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