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- W2024799624 abstract "Antimicrobial-induced mania, a rare but important side-effect of erythromycin and other drugs, is frequently under-recognized. Although its incidence - considering the wide use of antimicrobials - is statistically low, it should be regarded as a potential risk for patients both with and without a history of a mood disorder. Reports of manic reactions induced by antibiotics related mostly to new compounds have increased; a recent review on the topic, including published and non-published reports, found clarithromycin and ciprofloxacin to be the most frequently associated with the development of mania (Abouesh et al., 2002). Clarithromycin (Klaricid®) is an antibiotic useful in the treatment of upper and lower respiratory tract infections, local infections caused by MAC complex (Mycobacterium avium or M. intracellulare) and for the eradication of Helicobacter pylori. Common side-effects include nausea or vomiting, abdominal pain and diarrhoea. Rare side-effects include hepatitis, rash, anaphylaxis, Stevens-Johnson syndrome and ventricular arrhythmias. Side-effects to the central nervous system (CNS), which are not common, include anxiety, dizzness, disorientation, hallucination and insomnia. We report here a case of a manic reaction attributed to clarithromycin, in a patient without a previous clinically identified mood disorder." @default.
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- W2024799624 date "2004-03-01" @default.
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- W2024799624 title "A case of clarithromycin-induced manic episode (antibiomania)" @default.
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