FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2024800966> ?p ?o ?g. }

• W2024800966 endingPage "57" @default.
• W2024800966 startingPage "48" @default.
• W2024800966 abstract "<h2>Abstract</h2> We compared the effects of tempol (300μmolkg⁻¹ plus 300μmolkg⁻¹h⁻¹, <i>n</i>=14) and candesartan (10μgkg⁻¹ plus 10μgkg⁻¹h⁻¹, <i>n</i>=14) on renal haemodynamics, excretory function, and responses to electrical stimulation of the renal nerves (RNS) in lean and obese rabbits under pentobarbitone anaesthesia. Depressor responses to tempol (−16±2mmHg) and candesartan (−12±1mmHg) were similar. Candesartan, but not tempol, significantly increased basal renal blood flow (RBF; +36±7%). Tempol, but not candesartan, significantly reduced glomerular filtration rate (GFR; −30±10%) and sodium excretion (U_NaV; −44±14%). RNS induced frequency-dependent reductions in RBF (−20±3% at 1Hz), GFR (−28±6% at 1Hz) and U_NaV (−55±6% at 1Hz). Candesartan blunted these responses. Tempol did not significantly alter RBF and GFR responses to RNS but blunted the U_NaV response. Responses to RNS, and the effects of tempol and candesartan, were similar in lean compared with obese rabbits. Unlike candesartan, tempol did not induce renal vasodilatation, maintain GFR and U_NaV during reductions in arterial pressure, or blunt neurally-mediated vasoconstriction. In conclusion, unlike the AT₁-receptor antagonist candesartan, tempol does not blunt the effects of RNS on renal haemodynamic function. Furthermore, under the current experimental conditions superoxide appears to make little contribution to the actions of endogenous angiotensin II on baseline renal haemodynamics or excretory function, or their responses to RNS." @default.
• W2024800966 created "2016-06-24" @default.
• W2024800966 creator A5000045071 @default.
• W2024800966 creator A5012270101 @default.
• W2024800966 creator A5025133583 @default.
• W2024800966 creator A5063795274 @default.
• W2024800966 date "2012-05-01" @default.
• W2024800966 modified "2023-10-17" @default.
• W2024800966 title "Effects of tempol and candesartan on neural control of the kidney" @default.
• W2024800966 cites W1966173154 @default.
• W2024800966 cites W1972981377 @default.
• W2024800966 cites W1973071643 @default.
• W2024800966 cites W1975537177 @default.
• W2024800966 cites W1978680044 @default.
• W2024800966 cites W1979318323 @default.
• W2024800966 cites W1986121678 @default.
• W2024800966 cites W1987999845 @default.
• W2024800966 cites W2002094924 @default.
• W2024800966 cites W2007523611 @default.
• W2024800966 cites W2011200561 @default.
• W2024800966 cites W2046152126 @default.
• W2024800966 cites W2047217881 @default.
• W2024800966 cites W2052662416 @default.
• W2024800966 cites W2061544757 @default.
• W2024800966 cites W2063232675 @default.
• W2024800966 cites W2066500319 @default.
• W2024800966 cites W2069596838 @default.
• W2024800966 cites W2072776637 @default.
• W2024800966 cites W2073599743 @default.
• W2024800966 cites W2074540580 @default.
• W2024800966 cites W2081568683 @default.
• W2024800966 cites W2088913694 @default.
• W2024800966 cites W2093586784 @default.
• W2024800966 cites W2094855663 @default.
• W2024800966 cites W2095850917 @default.
• W2024800966 cites W2098930261 @default.
• W2024800966 cites W2102140304 @default.
• W2024800966 cites W2103128950 @default.
• W2024800966 cites W2103300387 @default.
• W2024800966 cites W2105226872 @default.
• W2024800966 cites W2114353702 @default.
• W2024800966 cites W2119592801 @default.
• W2024800966 cites W2123841491 @default.
• W2024800966 cites W2125060032 @default.
• W2024800966 cites W2126411455 @default.
• W2024800966 cites W2127873167 @default.
• W2024800966 cites W2131364281 @default.
• W2024800966 cites W2133924990 @default.
• W2024800966 cites W2135446787 @default.
• W2024800966 cites W2138538255 @default.
• W2024800966 cites W2139169410 @default.
• W2024800966 cites W2144826037 @default.
• W2024800966 cites W2145315506 @default.
• W2024800966 cites W2149062689 @default.
• W2024800966 cites W2153436347 @default.
• W2024800966 cites W2155227046 @default.
• W2024800966 cites W2167279474 @default.
• W2024800966 cites W2167563726 @default.
• W2024800966 cites W2170829905 @default.
• W2024800966 cites W2185943746 @default.
• W2024800966 cites W2322072338 @default.
• W2024800966 cites W2345181144 @default.
• W2024800966 cites W1950938391 @default.
• W2024800966 cites W2051567215 @default.
• W2024800966 doi "https://doi.org/10.1016/j.autneu.2012.01.007" @default.
• W2024800966 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22336580" @default.
• W2024800966 hasPublicationYear "2012" @default.
• W2024800966 type Work @default.
• W2024800966 sameAs 2024800966 @default.
• W2024800966 citedByCount "3" @default.
• W2024800966 countsByYear W20248009662013 @default.
• W2024800966 countsByYear W20248009662014 @default.
• W2024800966 crossrefType "journal-article" @default.
• W2024800966 hasAuthorship W2024800966A5000045071 @default.
• W2024800966 hasAuthorship W2024800966A5012270101 @default.
• W2024800966 hasAuthorship W2024800966A5025133583 @default.
• W2024800966 hasAuthorship W2024800966A5063795274 @default.
• W2024800966 hasConcept C120770815 @default.
• W2024800966 hasConcept C126322002 @default.
• W2024800966 hasConcept C134018914 @default.
• W2024800966 hasConcept C142225936 @default.
• W2024800966 hasConcept C159641895 @default.
• W2024800966 hasConcept C178853913 @default.
• W2024800966 hasConcept C185592680 @default.
• W2024800966 hasConcept C2779961880 @default.
• W2024800966 hasConcept C2780036600 @default.
• W2024800966 hasConcept C2780091579 @default.
• W2024800966 hasConcept C2780636983 @default.
• W2024800966 hasConcept C2908929049 @default.
• W2024800966 hasConcept C71924100 @default.
• W2024800966 hasConcept C84393581 @default.
• W2024800966 hasConceptScore W2024800966C120770815 @default.
• W2024800966 hasConceptScore W2024800966C126322002 @default.
• W2024800966 hasConceptScore W2024800966C134018914 @default.
• W2024800966 hasConceptScore W2024800966C142225936 @default.
• W2024800966 hasConceptScore W2024800966C159641895 @default.
• W2024800966 hasConceptScore W2024800966C178853913 @default.
• W2024800966 hasConceptScore W2024800966C185592680 @default.

• next