Matches in SemOpenAlex for { <https://semopenalex.org/work/W2024859904> ?p ?o ?g. }
- W2024859904 endingPage "1719" @default.
- W2024859904 startingPage "1712" @default.
- W2024859904 abstract "microRNAs (miRNAs) exist in blood in an apparently stable form. We have explored whether serum miRNAs can be used as non-invasive early biomarkers of colon cancer. Serum samples from 30 patients with colon cancer stage IV and 10 healthy controls were examined for the expression of 375 cancer-relevant miRNAs. Based on the miRNA profile in this study, 34 selected miRNAs were measured in serum from 40 patients with stage I–II colon cancer and from 10 additional controls. Twenty miRNAs were differentially expressed in serum from stage IV patients compared with controls (P<0.01). Unsupervised clustering revealed four subgroups; one corresponding mostly to the control group and the three others to the patient groups. Of the 34 miRNAs measured in the follow-up study of stage I–II patients, 21 showed concordant expression between stage IV and stage I–II patient. Based on the profiles of these 21 miRNAs, a supervised linear regression analysis (Partial Least Squares Regression) was performed. Using this model we correctly assigned stage I–II colon cancer patients based on miRNA profiles of stage IV patients. Serum miRNA expression profiling may be utilised in early detection of colon cancer." @default.
- W2024859904 created "2016-06-24" @default.
- W2024859904 creator A5014568853 @default.
- W2024859904 creator A5014746376 @default.
- W2024859904 creator A5018247006 @default.
- W2024859904 creator A5022297378 @default.
- W2024859904 creator A5025475046 @default.
- W2024859904 creator A5036456601 @default.
- W2024859904 creator A5063670944 @default.
- W2024859904 creator A5081864347 @default.
- W2024859904 creator A5087163244 @default.
- W2024859904 date "2013-04-01" @default.
- W2024859904 modified "2023-10-07" @default.
- W2024859904 title "Identification of serum microRNA profiles in colon cancer" @default.
- W2024859904 cites W1231469516 @default.
- W2024859904 cites W1485105189 @default.
- W2024859904 cites W1499305226 @default.
- W2024859904 cites W1969955808 @default.
- W2024859904 cites W1971588341 @default.
- W2024859904 cites W1977046582 @default.
- W2024859904 cites W1981055638 @default.
- W2024859904 cites W1987097208 @default.
- W2024859904 cites W1992481740 @default.
- W2024859904 cites W1992497862 @default.
- W2024859904 cites W1995799988 @default.
- W2024859904 cites W1996390519 @default.
- W2024859904 cites W2006535551 @default.
- W2024859904 cites W2007276591 @default.
- W2024859904 cites W2010449259 @default.
- W2024859904 cites W2015858554 @default.
- W2024859904 cites W2025635382 @default.
- W2024859904 cites W2028388552 @default.
- W2024859904 cites W2029348349 @default.
- W2024859904 cites W2030166934 @default.
- W2024859904 cites W2032923154 @default.
- W2024859904 cites W2034760388 @default.
- W2024859904 cites W2035213975 @default.
- W2024859904 cites W2038371585 @default.
- W2024859904 cites W2039164708 @default.
- W2024859904 cites W2046811422 @default.
- W2024859904 cites W2047146433 @default.
- W2024859904 cites W2047960154 @default.
- W2024859904 cites W2055313665 @default.
- W2024859904 cites W2058462008 @default.
- W2024859904 cites W2061888576 @default.
- W2024859904 cites W2063915996 @default.
- W2024859904 cites W2064251893 @default.
- W2024859904 cites W2066929317 @default.
- W2024859904 cites W2072356428 @default.
- W2024859904 cites W2080476488 @default.
- W2024859904 cites W2090635221 @default.
- W2024859904 cites W2094077020 @default.
- W2024859904 cites W2097233439 @default.
- W2024859904 cites W2103696805 @default.
- W2024859904 cites W2111471857 @default.
- W2024859904 cites W2113551318 @default.
- W2024859904 cites W2114015736 @default.
- W2024859904 cites W2115026470 @default.
- W2024859904 cites W2120887120 @default.
- W2024859904 cites W2124907137 @default.
- W2024859904 cites W2126513437 @default.
- W2024859904 cites W2131864553 @default.
- W2024859904 cites W2134747634 @default.
- W2024859904 cites W2135007926 @default.
- W2024859904 cites W2137980027 @default.
- W2024859904 cites W2139016888 @default.
- W2024859904 cites W2139528114 @default.
- W2024859904 cites W2140245250 @default.
- W2024859904 cites W2142139829 @default.
- W2024859904 cites W2142352901 @default.
- W2024859904 cites W2144149602 @default.
- W2024859904 cites W2153682544 @default.
- W2024859904 cites W2157197396 @default.
- W2024859904 cites W2159278398 @default.
- W2024859904 cites W2166046948 @default.
- W2024859904 cites W2168314151 @default.
- W2024859904 cites W2169045182 @default.
- W2024859904 cites W2262414037 @default.
- W2024859904 cites W2302039093 @default.
- W2024859904 doi "https://doi.org/10.1038/bjc.2013.121" @default.
- W2024859904 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3668463" @default.
- W2024859904 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23558896" @default.
- W2024859904 hasPublicationYear "2013" @default.
- W2024859904 type Work @default.
- W2024859904 sameAs 2024859904 @default.
- W2024859904 citedByCount "72" @default.
- W2024859904 countsByYear W20248599042013 @default.
- W2024859904 countsByYear W20248599042014 @default.
- W2024859904 countsByYear W20248599042015 @default.
- W2024859904 countsByYear W20248599042016 @default.
- W2024859904 countsByYear W20248599042017 @default.
- W2024859904 countsByYear W20248599042018 @default.
- W2024859904 countsByYear W20248599042019 @default.
- W2024859904 countsByYear W20248599042020 @default.
- W2024859904 countsByYear W20248599042021 @default.
- W2024859904 countsByYear W20248599042022 @default.
- W2024859904 countsByYear W20248599042023 @default.
- W2024859904 crossrefType "journal-article" @default.