Matches in SemOpenAlex for { <https://semopenalex.org/work/W2024861987> ?p ?o ?g. }
Showing items 1 to 90 of
90
with 100 items per page.
- W2024861987 endingPage "94" @default.
- W2024861987 startingPage "89" @default.
- W2024861987 abstract "Background: Soluble urokinase plasminogen activator receptor (suPAR) is released in response to inflammatory stimuli, and plasma levels are associated with long-term outcomes. The ischemia/reperfusion injury caused by cardiac arrest (CA) and resuscitation triggers an inflammatory response. This pilot study aimed at investigating suPAR levels in relation to outcome after CA and mild induced hypothermia. Methods: suPAR levels were measured at 6, 36, and 72 hours in patients treated with hypothermia after CA. suPAR levels were analyzed in relation to survival after 6 months. Receiver operating characteristic curve (ROC)-analyses were performed, and area under the curve (AUC) was calculated. Time to return of spontaneous circulation (ROSC) was correlated to suPAR levels. Results: Fifty-five patients (40 male, median 65 years) were included, and 33 (60%) were alive after 6 months. The suPAR levels were significantly higher in nonsurviving patients compared with survivors at 6 and 36 hours (p=0.006 and 0.034 respectively), but not at 72 hours. The suPAR levels increased from 6 to 72 hours (p<0.0001). Time to ROSC correlated positively with suPAR levels at 6 hours (p=0.003) but not at 36 and 72 hours. ROC analysis shoved an AUC of 0.76 at 6 hours. In the subgroup of CA of cardiac cause, the AUC was 0.84. Conclusion: suPAR levels at 6 and 36 hours after CA were significantly higher in nonsurviving patients compared with survivors; however, the overlap in suPAR levels between the outcome groups was substantial, reducing the prognostic value. There was a significant increase in suPAR levels during the first 72 hours after CA." @default.
- W2024861987 created "2016-06-24" @default.
- W2024861987 creator A5013780146 @default.
- W2024861987 creator A5016811769 @default.
- W2024861987 creator A5027175571 @default.
- W2024861987 creator A5028430735 @default.
- W2024861987 date "2015-06-01" @default.
- W2024861987 modified "2023-10-16" @default.
- W2024861987 title "The Inflammatory Marker suPAR After Cardiac Arrest" @default.
- W2024861987 cites W1514221498 @default.
- W2024861987 cites W1569358024 @default.
- W2024861987 cites W1874700596 @default.
- W2024861987 cites W1971073682 @default.
- W2024861987 cites W1989659901 @default.
- W2024861987 cites W1998807587 @default.
- W2024861987 cites W2000258296 @default.
- W2024861987 cites W2004880314 @default.
- W2024861987 cites W2006693793 @default.
- W2024861987 cites W2040443712 @default.
- W2024861987 cites W2043754323 @default.
- W2024861987 cites W2076252741 @default.
- W2024861987 cites W2086595076 @default.
- W2024861987 cites W2087245829 @default.
- W2024861987 cites W2101713406 @default.
- W2024861987 cites W2103989414 @default.
- W2024861987 cites W2109323060 @default.
- W2024861987 cites W2122828189 @default.
- W2024861987 cites W2132828093 @default.
- W2024861987 cites W2162420606 @default.
- W2024861987 cites W4213186691 @default.
- W2024861987 cites W81660439 @default.
- W2024861987 doi "https://doi.org/10.1089/ther.2014.0027" @default.
- W2024861987 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25695339" @default.
- W2024861987 hasPublicationYear "2015" @default.
- W2024861987 type Work @default.
- W2024861987 sameAs 2024861987 @default.
- W2024861987 citedByCount "10" @default.
- W2024861987 countsByYear W20248619872016 @default.
- W2024861987 countsByYear W20248619872017 @default.
- W2024861987 countsByYear W20248619872019 @default.
- W2024861987 countsByYear W20248619872020 @default.
- W2024861987 countsByYear W20248619872021 @default.
- W2024861987 countsByYear W20248619872023 @default.
- W2024861987 crossrefType "journal-article" @default.
- W2024861987 hasAuthorship W2024861987A5013780146 @default.
- W2024861987 hasAuthorship W2024861987A5016811769 @default.
- W2024861987 hasAuthorship W2024861987A5027175571 @default.
- W2024861987 hasAuthorship W2024861987A5028430735 @default.
- W2024861987 hasConcept C126322002 @default.
- W2024861987 hasConcept C2776892390 @default.
- W2024861987 hasConcept C2776929539 @default.
- W2024861987 hasConcept C2777390192 @default.
- W2024861987 hasConcept C42219234 @default.
- W2024861987 hasConcept C56219504 @default.
- W2024861987 hasConcept C58471807 @default.
- W2024861987 hasConcept C71924100 @default.
- W2024861987 hasConcept C76318530 @default.
- W2024861987 hasConcept C90924648 @default.
- W2024861987 hasConceptScore W2024861987C126322002 @default.
- W2024861987 hasConceptScore W2024861987C2776892390 @default.
- W2024861987 hasConceptScore W2024861987C2776929539 @default.
- W2024861987 hasConceptScore W2024861987C2777390192 @default.
- W2024861987 hasConceptScore W2024861987C42219234 @default.
- W2024861987 hasConceptScore W2024861987C56219504 @default.
- W2024861987 hasConceptScore W2024861987C58471807 @default.
- W2024861987 hasConceptScore W2024861987C71924100 @default.
- W2024861987 hasConceptScore W2024861987C76318530 @default.
- W2024861987 hasConceptScore W2024861987C90924648 @default.
- W2024861987 hasIssue "2" @default.
- W2024861987 hasLocation W20248619871 @default.
- W2024861987 hasLocation W20248619872 @default.
- W2024861987 hasOpenAccess W2024861987 @default.
- W2024861987 hasPrimaryLocation W20248619871 @default.
- W2024861987 hasRelatedWork W2085454302 @default.
- W2024861987 hasRelatedWork W2157657209 @default.
- W2024861987 hasRelatedWork W2484458077 @default.
- W2024861987 hasRelatedWork W2498441064 @default.
- W2024861987 hasRelatedWork W2905398573 @default.
- W2024861987 hasRelatedWork W2989916819 @default.
- W2024861987 hasRelatedWork W3109446658 @default.
- W2024861987 hasRelatedWork W3210128647 @default.
- W2024861987 hasRelatedWork W4280549677 @default.
- W2024861987 hasRelatedWork W4378953810 @default.
- W2024861987 hasVolume "5" @default.
- W2024861987 isParatext "false" @default.
- W2024861987 isRetracted "false" @default.
- W2024861987 magId "2024861987" @default.
- W2024861987 workType "article" @default.