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- W2024871981 abstract "Amyloid precursor protein generates the β-amyloid peptide and is a member of a multigene family that contains at least two other gene products, known as amyloid precursor-like proteins. Heme oxygenase is an enzyme whose products are antioxidant and neuroprotective. The authors report that amyloid precursor protein and amyloid precursor-like protein bind to heme oxygenase to inhibit its enzymatic activity. Our findings suggest that decreased neuroprotection caused by amyloid precursor protein–heme oxygenase interactions influences neurotoxicity in Alzheimer disease." @default.
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- W2024871981 date "2000-01-01" @default.
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- W2024871981 title "Interaction of Amyloid Precursor Proteins and Heme Oxygenase" @default.
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- W2024871981 doi "https://doi.org/10.1097/00002093-200000001-00011" @default.
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