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• W2024880844 startingPage "157" @default.
• W2024880844 abstract "The evidence for polycyclic aromatic hydrocarbons (PAH) playing a role in prostate carcinogenesis comes mainly from associations between reported PAH exposures and prostate cancer in epidemiologic studies. Associations between prostate cancer and DNA repair genotypes and phenotypes have also been reported, lending further credence to a PAH-induced carcinogenesis pathway in prostate cancer. Recent work that demonstrates the human prostate has metabolic enzyme activity necessary for PAH activation and will form DNA adducts upon exposure to PAH further supports PAH carcinogenesis. We have demonstrated the presence of PAH-DNA adducts in prostate cancer cases, but further validation of this biomarker as a carcinogenic agent in human prostate is needed." @default.
• W2024880844 created "2016-06-24" @default.
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• W2024880844 creator A5068592569 @default.
• W2024880844 creator A5085688534 @default.
• W2024880844 creator A5087780392 @default.
• W2024880844 date "2006-08-01" @default.
• W2024880844 modified "2023-10-18" @default.
• W2024880844 title "Polycyclic aromatic hydrocarbon-DNA adduct formation in prostate carcinogenesis" @default.
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• W2024880844 doi "https://doi.org/10.1016/j.canlet.2005.07.029" @default.
• W2024880844 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1761147" @default.
• W2024880844 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16154258" @default.
• W2024880844 hasPublicationYear "2006" @default.
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