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- W2024883661 abstract "Clinical, metabolic, and pathologic studies of a patient with advanced morbus caeruleus (tetralogy of Fallot) are reported. The patient died at the age of 19, and had been cyanosed since the age of 2. He was proficient scholastically, and, until a year before death, suffered a minimum of handicap from his malady. He was thought to have had rheumatic fever at the age of 9 and subacute bacterial endocarditis during his last year of life. A colon bacillus abscess of the cerebrum was immediately responsible for death.The metabolic investigations revealed a profound variation from the normal in the acid-base equilibrium of the body, and changes in renal function. As much as 75 per cent of the blood in the cardiac chambers was thought to traverse a right-to-left shunt. The oxygen saturation of the arterial blood varied between 62 and 58 per cent. These are critical levels for human existence. The oxygen capacity was about 35 volumes per cent. The carbon dioxide content of the arterial blood was less than 33 volumes per cent. The arterial pHs was less than 7.29. A profound, uncompensated acidosis was attributed to the increased concentration of undetermined acids and failure of the respiratory center to maintain the usual balance between free and combined carbon dioxide. The functional insufficiency of the kidneys was attributed to anoxemia, venous congestion, and acidosis." @default.
- W2024883661 created "2016-06-24" @default.
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- W2024883661 date "1937-08-01" @default.
- W2024883661 modified "2023-09-24" @default.
- W2024883661 title "Apparent increased velocity of blood flow in cases of congenital heart disease with septal defects having right-to-left shunt" @default.
- W2024883661 cites W2000380045 @default.
- W2024883661 doi "https://doi.org/10.1016/s0002-8703(37)91318-8" @default.
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