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- W2024886900 abstract "This paper presents a post hoc analysis of a recent large, 12-week, placebo-controlled trial of paroxetine in the treatment of social phobia, which analyzes subgroups of patients classified as suffering from severe (Liebowitz Social Anxiety Scale [LSAS] total score ≥82, n=85) or moderate (LSAS total score 52–81, n=78) social phobia. With respect to the reduction in LSAS total score, the paroxetine-placebo difference was greater in patients in the severe subgroup (20.0, P<0.001) than those in the moderate subgroup (13.7, P<0.02). Likewise, for the number of patients rated as `very much' or `much' improved according to their Clinical Global Impressions improvement scores, the paroxetine–placebo difference was greater in the severe subgroup (34.2%, P<0.001) than in the moderate subgroup (29.1%, P<0.02). In conclusion, paroxetine is effective compared with placebo in both moderate and severe social phobia, and the response is more clear cut in patients with more severe symptoms." @default.
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- W2024886900 title "Implications of the severity of social phobia" @default.
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- W2024886900 doi "https://doi.org/10.1016/s0165-0327(98)00093-7" @default.
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