FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2024896016> ?p ?o ?g. }

• W2024896016 endingPage "146" @default.
• W2024896016 startingPage "138" @default.
• W2024896016 abstract "Antipsychotic polypharmacy and excessive dosing still prevail worldwide in the treatment of schizophrenia, while their possible association with cognitive function has not well been examined. We examined whether the “non-standard” use of antipsychotics (defined as antipsychotic polypharmacy or dosage > 1000 mg/day of chlorpromazine equivalents) is associated with cognitive function. Furthermore, we compared cognitive function between patients taking only atypical antipsychotics and those taking only conventionals. Neurocognitive functions were assessed in 67 patients with chronic schizophrenia and 92 controls using the Wechsler Memory Scale-Revised (WMS-R), the Wechsler Adult Intelligence Scale-Revised (WAIS-R), the Wisconsin Card Sorting Test (WCST), and the Advanced Trail Making Test (ATMT). Patients showed markedly poorer performance than controls on all these tests. Patients on non-standard antipsychotic medication demonstrated poorer performance than those on standard medication on visual memory, delayed recall, performance IQ, and executive function. Patients taking atypical antipsychotics showed better performance than those taking conventionals on visual memory, delayed recall, and executive function. Clinical characteristics such as duration of medication, number of hospitalizations, and concomitant antiparkinsonian drugs were different between the treatment groups (both dichotomies of standard/non-standard and conventional/atypical). These results provide evidence for an association between antipsychotic medication and cognitive function. This association between antipsychotic medication and cognitive function may be due to differential illness severity (e.g., non-standard treatment for severely ill patients who have severe cognitive impairment). Alternatively, poorer cognitive function may be due in part to polypharmacy or excessive dosing. Further investigations are required to draw any conclusions." @default.
• W2024896016 created "2016-06-24" @default.
• W2024896016 creator A5021063513 @default.
• W2024896016 creator A5028402998 @default.
• W2024896016 creator A5049786069 @default.
• W2024896016 creator A5050344165 @default.
• W2024896016 creator A5051913745 @default.
• W2024896016 creator A5054212150 @default.
• W2024896016 creator A5062165699 @default.
• W2024896016 creator A5065211273 @default.
• W2024896016 creator A5067999904 @default.
• W2024896016 creator A5072006202 @default.
• W2024896016 creator A5072766543 @default.
• W2024896016 creator A5074094440 @default.
• W2024896016 creator A5081512560 @default.
• W2024896016 creator A5087761372 @default.
• W2024896016 creator A5090292944 @default.
• W2024896016 creator A5091016342 @default.
• W2024896016 date "2006-09-01" @default.
• W2024896016 modified "2023-10-15" @default.
• W2024896016 title "Antipsychotic medication and cognitive function in schizophrenia" @default.
• W2024896016 cites W12519945 @default.
• W2024896016 cites W1616286551 @default.
• W2024896016 cites W1657694742 @default.
• W2024896016 cites W1967377279 @default.
• W2024896016 cites W1975232812 @default.
• W2024896016 cites W1976012472 @default.
• W2024896016 cites W1983861222 @default.
• W2024896016 cites W1992097472 @default.
• W2024896016 cites W2003241894 @default.
• W2024896016 cites W2003826675 @default.
• W2024896016 cites W2005971050 @default.
• W2024896016 cites W2012392700 @default.
• W2024896016 cites W2012578747 @default.
• W2024896016 cites W2014531725 @default.
• W2024896016 cites W2018972399 @default.
• W2024896016 cites W2024631549 @default.
• W2024896016 cites W2029231999 @default.
• W2024896016 cites W2029440888 @default.
• W2024896016 cites W2031364731 @default.
• W2024896016 cites W2033177370 @default.
• W2024896016 cites W2035261866 @default.
• W2024896016 cites W2036410804 @default.
• W2024896016 cites W2036966602 @default.
• W2024896016 cites W2041495183 @default.
• W2024896016 cites W2052401826 @default.
• W2024896016 cites W2057964653 @default.
• W2024896016 cites W2058909881 @default.
• W2024896016 cites W2074064132 @default.
• W2024896016 cites W2075415557 @default.
• W2024896016 cites W2081011308 @default.
• W2024896016 cites W2081893917 @default.
• W2024896016 cites W2090441238 @default.
• W2024896016 cites W2094381093 @default.
• W2024896016 cites W2103782573 @default.
• W2024896016 cites W2105421068 @default.
• W2024896016 cites W2106352416 @default.
• W2024896016 cites W2106799594 @default.
• W2024896016 cites W2110569861 @default.
• W2024896016 cites W2121113553 @default.
• W2024896016 cites W2122206301 @default.
• W2024896016 cites W2122697202 @default.
• W2024896016 cites W2140249810 @default.
• W2024896016 cites W2140606211 @default.
• W2024896016 cites W2143830678 @default.
• W2024896016 cites W2145056060 @default.
• W2024896016 cites W2149805979 @default.
• W2024896016 cites W2150155552 @default.
• W2024896016 cites W2150174494 @default.
• W2024896016 cites W2151716318 @default.
• W2024896016 cites W2156114009 @default.
• W2024896016 cites W2159392121 @default.
• W2024896016 cites W2161441553 @default.
• W2024896016 cites W2162052901 @default.
• W2024896016 cites W2166192486 @default.
• W2024896016 cites W2324336452 @default.
• W2024896016 cites W31690976 @default.
• W2024896016 cites W4254216202 @default.
• W2024896016 cites W88231780 @default.
• W2024896016 doi "https://doi.org/10.1016/j.schres.2006.05.004" @default.
• W2024896016 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16793238" @default.
• W2024896016 hasPublicationYear "2006" @default.
• W2024896016 type Work @default.
• W2024896016 sameAs 2024896016 @default.
• W2024896016 citedByCount "116" @default.
• W2024896016 countsByYear W20248960162012 @default.
• W2024896016 countsByYear W20248960162013 @default.
• W2024896016 countsByYear W20248960162014 @default.
• W2024896016 countsByYear W20248960162015 @default.
• W2024896016 countsByYear W20248960162016 @default.
• W2024896016 countsByYear W20248960162017 @default.
• W2024896016 countsByYear W20248960162018 @default.
• W2024896016 countsByYear W20248960162019 @default.
• W2024896016 countsByYear W20248960162020 @default.
• W2024896016 countsByYear W20248960162021 @default.
• W2024896016 countsByYear W20248960162022 @default.
• W2024896016 countsByYear W20248960162023 @default.
• W2024896016 crossrefType "journal-article" @default.

• next