FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2024896551> ?p ?o ?g. }

• W2024896551 endingPage "386" @default.
• W2024896551 startingPage "383" @default.
• W2024896551 abstract "Over-expression of the c-erbB-2 oncogene-encoded p185 protein product has been implicated in the pathogenesis of a wide variety of human malignancies, including lung cancer. Over-expression of p185 can be detected immunologically by quantification of the extracellular domain of p185 (c-erbB-2 oncopeptide) in extracellular fluid in vitro and in serum in vivo. An enzyme-linked immunosorbent assay (ELISA) for the c-erbB-2 oncopeptide was used to examine banked serum samples of 11 pneumoconiosis patients who subsequently developed lung cancer and serum samples from 11 hospital controls matched for age, sex, ethnic group and smoking as well as 55 unmatched general population controls. The mean serum level for the c-erbB-2 oncopeptide in human neu units/ml in the lung cancer cases (1,756 +/- 549 HNU/ml) was statistically significantly elevated (p < 0.001) in comparison to the mean level in the matched controls (976 +/- 488 HNU/ml) or the general population controls (888 +/- 655 HNU/ml). Defining a positive elevation of the serum c-erbB-2 oncopeptide as any value more than 2 standard deviations above the mean of the matched controls, 64% (7 of 11) of the lung cancer cases were positive compared to 0% (0 of 11) matched controls and 5% (3 of 55) of the unmatched controls. In addition, 4 of the 7 c-erbB-2 oncopeptide-positive cancer cases had positive serum samples prior to the time of disease diagnosis (average = 35 months). These results suggest that serum c-erbB-2 oncopeptide may be elevated at an early stage of pulmonary carcinogenesis and that further prospective study of the utility of this biomarker is warranted." @default.
• W2024896551 created "2016-06-24" @default.
• W2024896551 creator A5011518228 @default.
• W2024896551 creator A5016807540 @default.
• W2024896551 creator A5045500968 @default.
• W2024896551 creator A5051230211 @default.
• W2024896551 creator A5056784159 @default.
• W2024896551 creator A5058753458 @default.
• W2024896551 creator A5079220096 @default.
• W2024896551 creator A5082554584 @default.
• W2024896551 creator A5082879564 @default.
• W2024896551 creator A5090212645 @default.
• W2024896551 date "1994-02-01" @default.
• W2024896551 modified "2023-10-01" @default.
• W2024896551 title "Detection of increased amounts of the extracellular domain of the c-erbB-2 oncoprotein in serum during pulmonary carcinogenesis in humans" @default.
• W2024896551 cites W1491740602 @default.
• W2024896551 cites W1999828947 @default.
• W2024896551 cites W2019091902 @default.
• W2024896551 cites W2033030726 @default.
• W2024896551 cites W2050238066 @default.
• W2024896551 cites W2050411049 @default.
• W2024896551 cites W2051431808 @default.
• W2024896551 cites W2051693909 @default.
• W2024896551 cites W2058106485 @default.
• W2024896551 cites W2156958504 @default.
• W2024896551 cites W2199607744 @default.
• W2024896551 doi "https://doi.org/10.1002/ijc.2910560316" @default.
• W2024896551 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7906254" @default.
• W2024896551 hasPublicationYear "1994" @default.
• W2024896551 type Work @default.
• W2024896551 sameAs 2024896551 @default.
• W2024896551 citedByCount "43" @default.
• W2024896551 countsByYear W20248965512013 @default.
• W2024896551 countsByYear W20248965512019 @default.
• W2024896551 countsByYear W20248965512020 @default.
• W2024896551 crossrefType "journal-article" @default.
• W2024896551 hasAuthorship W2024896551A5011518228 @default.
• W2024896551 hasAuthorship W2024896551A5016807540 @default.
• W2024896551 hasAuthorship W2024896551A5045500968 @default.
• W2024896551 hasAuthorship W2024896551A5051230211 @default.
• W2024896551 hasAuthorship W2024896551A5056784159 @default.
• W2024896551 hasAuthorship W2024896551A5058753458 @default.
• W2024896551 hasAuthorship W2024896551A5079220096 @default.
• W2024896551 hasAuthorship W2024896551A5082554584 @default.
• W2024896551 hasAuthorship W2024896551A5082879564 @default.
• W2024896551 hasAuthorship W2024896551A5090212645 @default.
• W2024896551 hasConcept C121608353 @default.
• W2024896551 hasConcept C126322002 @default.
• W2024896551 hasConcept C134018914 @default.
• W2024896551 hasConcept C142724271 @default.
• W2024896551 hasConcept C146304588 @default.
• W2024896551 hasConcept C203014093 @default.
• W2024896551 hasConcept C2776178081 @default.
• W2024896551 hasConcept C2776256026 @default.
• W2024896551 hasConcept C2777714996 @default.
• W2024896551 hasConcept C2780942790 @default.
• W2024896551 hasConcept C2781018059 @default.
• W2024896551 hasConcept C28406088 @default.
• W2024896551 hasConcept C2908647359 @default.
• W2024896551 hasConcept C29537977 @default.
• W2024896551 hasConcept C54355233 @default.
• W2024896551 hasConcept C555283112 @default.
• W2024896551 hasConcept C71924100 @default.
• W2024896551 hasConcept C86803240 @default.
• W2024896551 hasConcept C90924648 @default.
• W2024896551 hasConcept C99454951 @default.
• W2024896551 hasConceptScore W2024896551C121608353 @default.
• W2024896551 hasConceptScore W2024896551C126322002 @default.
• W2024896551 hasConceptScore W2024896551C134018914 @default.
• W2024896551 hasConceptScore W2024896551C142724271 @default.
• W2024896551 hasConceptScore W2024896551C146304588 @default.
• W2024896551 hasConceptScore W2024896551C203014093 @default.
• W2024896551 hasConceptScore W2024896551C2776178081 @default.
• W2024896551 hasConceptScore W2024896551C2776256026 @default.
• W2024896551 hasConceptScore W2024896551C2777714996 @default.
• W2024896551 hasConceptScore W2024896551C2780942790 @default.
• W2024896551 hasConceptScore W2024896551C2781018059 @default.
• W2024896551 hasConceptScore W2024896551C28406088 @default.
• W2024896551 hasConceptScore W2024896551C2908647359 @default.
• W2024896551 hasConceptScore W2024896551C29537977 @default.
• W2024896551 hasConceptScore W2024896551C54355233 @default.
• W2024896551 hasConceptScore W2024896551C555283112 @default.
• W2024896551 hasConceptScore W2024896551C71924100 @default.
• W2024896551 hasConceptScore W2024896551C86803240 @default.
• W2024896551 hasConceptScore W2024896551C90924648 @default.
• W2024896551 hasConceptScore W2024896551C99454951 @default.
• W2024896551 hasIssue "3" @default.
• W2024896551 hasLocation W20248965511 @default.
• W2024896551 hasLocation W20248965512 @default.
• W2024896551 hasOpenAccess W2024896551 @default.
• W2024896551 hasPrimaryLocation W20248965511 @default.
• W2024896551 hasRelatedWork W1930767791 @default.
• W2024896551 hasRelatedWork W1938011709 @default.
• W2024896551 hasRelatedWork W2056966621 @default.
• W2024896551 hasRelatedWork W2068095727 @default.
• W2024896551 hasRelatedWork W2094242781 @default.
• W2024896551 hasRelatedWork W2129989483 @default.
• W2024896551 hasRelatedWork W2271907559 @default.

• next