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- W2024896727 abstract "One of the most important factors in laser therapy is the dose. In the literature we find that the usually is defined as the amount of energy applied to 1 cm 2 of skin. In this presentation we will look closer on what we mean with dose and what happens to the energy brought into the tissue. What is the 1 cm down in tissue? Should the unit instead be joules per cm 3 , or, would it be better using joules per mm 3 . In a blood vessel under an illuminated square centimeter of skin, we might perhaps use joules per ml. The light gives both local effects on cells and tissue and systemic effects - which is the most dominating? The energy that we feed into the tissue will cause a three dimensional light intensity distribution with different values in different points. In a static situation we will have the same distribution growing linearly with exposure time. In the case of coherent light illumination, a three dimensional speckle field is created and locally the energy density is varying a lot from point to point, causing field gradients. In some points of the illuminated volume, the might be so high that retarding effects may occur while in other, the may be close to zero. The situation is different for in vitro situation, for treatment of open wounds, for entering the light via a fiber in a syringe, for using super pulsed light sources etc. For wavelengths with very low tissue penetration the situation is different." @default.
- W2024896727 created "2016-06-24" @default.
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- W2024896727 date "2006-02-09" @default.
- W2024896727 modified "2023-09-23" @default.
- W2024896727 title "Some new aspects of the dose in laser therapy" @default.
- W2024896727 doi "https://doi.org/10.1117/12.640925" @default.
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