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- W2024898516 abstract "A case of iodide-induced goiter and myxedema is presented. Radioiodine studies in this patient demonstrated a rapid thyroidal accumulation of tracer which could be discharged by thiocyanate. An increased thyroid-plasma gradient, as reflected by an enlarged thyroidal iodide space, was also demonstrated. Thirty-two published case reports of presumed iodide-induced myxedema and goiter are reviewed. The cases are classified according to the thyroidal status prior to the onset of iodine ingestion. The theoretic basis of this syndrome is discussed. It is concluded that the development of goiter and myxedema depends either upon the length and regularity of iodide ingestion or upon a basic sensitivity to iodides, possibly related to some pre-existent subtle defect in intrathyroidal metabolism. The clinical and laboratory criteria for the diagnosis of this syndrome are tentatively defined." @default.
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- W2024898516 title "The syndrome of iodide-induced goiter and myxedema" @default.
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- W2024898516 doi "https://doi.org/10.1016/0002-9343(61)90099-7" @default.
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