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- W2024916326 abstract "Abstract HCE was metabolised to a monohydroxy epoxide (HHC) by liver microsomes and 11,000g supernatants of the rat, rabbit, pigeon and Japanese quail. After a substantial amount of the substrate had been metabolised HHC began to be hydroxylated to a more polar metabolite that was identified as dihydroxy HCE. Both metabolic conversions were evidently mixed function oxidations since they depended upon NADPH and O2. Dihydroxy HCE was also produced in vivo by the rabbit and the quail." @default.
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- W2024916326 date "1973-09-01" @default.
- W2024916326 modified "2023-09-27" @default.
- W2024916326 title "Metabolism of a dieldrin analogue - secondary oxidation by liver microsomes" @default.
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- W2024916326 doi "https://doi.org/10.1016/0024-3205(73)90051-9" @default.
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