FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2024946537> ?p ?o ?g. }

• W2024946537 endingPage "228" @default.
• W2024946537 startingPage "224" @default.
• W2024946537 abstract "Carboxylesterase (CarE)-mediated detoxification is one of the most important mediators of resistance to organophosphate insecticides (OPs). However, the molecular mechanisms by which CarEs mediate OP resistance are largely unknown. Our previous studies indicated that increased CarE activity was critical for chlorpyrifos (an OP) resistance in Laodelphax striatellus. In this study, 28 CarE and CarE-like genes (CarEs) were identified in the transcriptome of L. striatellus. Real-time quantitative PCR (qPCR) was performed to assess the relative expression of these 28 CarEs. Compared with the susceptible (YN) strain, Ls.CarE1 and Ls.CarE2 were significantly overexpressed in the chlorpyrifos-resistant (YN-CPF) strain by 32.06- and 8.52-fold, respectively. The expression levels of Ls.CarE1 and Ls.CarE2 were analyzed by qPCR to verify the correlation between overexpressed CarEs in the YN-CPF strain and chlorpyrifos resistance. Chlorpyrifos bioassays and CarE activity assays were subsequently performed on the chlorpyrifos relaxed selection (YN-RSF) strain. The results demonstrated that CarE activity was significantly higher in the YN-CPF and YN-RSF strains (4.15- and 1.92-fold, respectively) than in the YN strain, which was consistent with their respective degrees of chlorpyrifos resistance (214.0-fold for YN-CPF and 83.3-fold for YN-RSF). Ls.CarE1 was significantly overexpressed in both the YN-CPF and the YN-RSF strains (32.06-fold for YN-CPF and 8.6-fold for YN-RSF) compared with the YN strain, and a high degree of proportionality was observed between the expression level of Ls.CarE1 and the degree of resistance to chlorpyrifos across the three strains. However, the expression level of Ls.CarE2 in the YN-RSF and the YN strains was not significantly different. These data suggest that overexpressed Ls.CarE1 might be involved in chlorpyrifos resistance in the YN-CPF strain of L. striatellus." @default.
• W2024946537 created "2016-06-24" @default.
• W2024946537 creator A5000248061 @default.
• W2024946537 creator A5004441169 @default.
• W2024946537 creator A5015724857 @default.
• W2024946537 creator A5031741004 @default.
• W2024946537 creator A5040215906 @default.
• W2024946537 creator A5076014683 @default.
• W2024946537 creator A5090063930 @default.
• W2024946537 date "2012-11-01" @default.
• W2024946537 modified "2023-10-06" @default.
• W2024946537 title "A transcriptome-based screen of carboxylesterase-like genes that are involved in chlorpyrifos resistance in Laodelphax striatellus (Fallén)" @default.
• W2024946537 cites W1583547308 @default.
• W2024946537 cites W1952776096 @default.
• W2024946537 cites W1983025754 @default.
• W2024946537 cites W1991937846 @default.
• W2024946537 cites W1993037853 @default.
• W2024946537 cites W1998660701 @default.
• W2024946537 cites W2010112658 @default.
• W2024946537 cites W2018295168 @default.
• W2024946537 cites W2034402236 @default.
• W2024946537 cites W2043789665 @default.
• W2024946537 cites W2072115605 @default.
• W2024946537 cites W2073305407 @default.
• W2024946537 cites W2085825040 @default.
• W2024946537 cites W2107277218 @default.
• W2024946537 cites W2115669862 @default.
• W2024946537 cites W2117188933 @default.
• W2024946537 cites W2123325948 @default.
• W2024946537 cites W2126506685 @default.
• W2024946537 cites W2155463517 @default.
• W2024946537 cites W2209681935 @default.
• W2024946537 doi "https://doi.org/10.1016/j.pestbp.2012.08.006" @default.
• W2024946537 hasPublicationYear "2012" @default.
• W2024946537 type Work @default.
• W2024946537 sameAs 2024946537 @default.
• W2024946537 citedByCount "15" @default.
• W2024946537 countsByYear W20249465372013 @default.
• W2024946537 countsByYear W20249465372015 @default.
• W2024946537 countsByYear W20249465372016 @default.
• W2024946537 countsByYear W20249465372017 @default.
• W2024946537 countsByYear W20249465372018 @default.
• W2024946537 countsByYear W20249465372019 @default.
• W2024946537 countsByYear W20249465372020 @default.
• W2024946537 countsByYear W20249465372021 @default.
• W2024946537 countsByYear W20249465372022 @default.
• W2024946537 countsByYear W20249465372023 @default.
• W2024946537 crossrefType "journal-article" @default.
• W2024946537 hasAuthorship W2024946537A5000248061 @default.
• W2024946537 hasAuthorship W2024946537A5004441169 @default.
• W2024946537 hasAuthorship W2024946537A5015724857 @default.
• W2024946537 hasAuthorship W2024946537A5031741004 @default.
• W2024946537 hasAuthorship W2024946537A5040215906 @default.
• W2024946537 hasAuthorship W2024946537A5076014683 @default.
• W2024946537 hasAuthorship W2024946537A5090063930 @default.
• W2024946537 hasConcept C104317684 @default.
• W2024946537 hasConcept C104488531 @default.
• W2024946537 hasConcept C105702510 @default.
• W2024946537 hasConcept C150194340 @default.
• W2024946537 hasConcept C153911025 @default.
• W2024946537 hasConcept C161176658 @default.
• W2024946537 hasConcept C162317418 @default.
• W2024946537 hasConcept C181199279 @default.
• W2024946537 hasConcept C2776304672 @default.
• W2024946537 hasConcept C2776588719 @default.
• W2024946537 hasConcept C2778022156 @default.
• W2024946537 hasConcept C2778325069 @default.
• W2024946537 hasConcept C54355233 @default.
• W2024946537 hasConcept C55493867 @default.
• W2024946537 hasConcept C6557445 @default.
• W2024946537 hasConcept C86803240 @default.
• W2024946537 hasConcept C98274493 @default.
• W2024946537 hasConceptScore W2024946537C104317684 @default.
• W2024946537 hasConceptScore W2024946537C104488531 @default.
• W2024946537 hasConceptScore W2024946537C105702510 @default.
• W2024946537 hasConceptScore W2024946537C150194340 @default.
• W2024946537 hasConceptScore W2024946537C153911025 @default.
• W2024946537 hasConceptScore W2024946537C161176658 @default.
• W2024946537 hasConceptScore W2024946537C162317418 @default.
• W2024946537 hasConceptScore W2024946537C181199279 @default.
• W2024946537 hasConceptScore W2024946537C2776304672 @default.
• W2024946537 hasConceptScore W2024946537C2776588719 @default.
• W2024946537 hasConceptScore W2024946537C2778022156 @default.
• W2024946537 hasConceptScore W2024946537C2778325069 @default.
• W2024946537 hasConceptScore W2024946537C54355233 @default.
• W2024946537 hasConceptScore W2024946537C55493867 @default.
• W2024946537 hasConceptScore W2024946537C6557445 @default.
• W2024946537 hasConceptScore W2024946537C86803240 @default.
• W2024946537 hasConceptScore W2024946537C98274493 @default.
• W2024946537 hasIssue "3" @default.
• W2024946537 hasLocation W20249465371 @default.
• W2024946537 hasOpenAccess W2024946537 @default.
• W2024946537 hasPrimaryLocation W20249465371 @default.
• W2024946537 hasRelatedWork W1970226733 @default.
• W2024946537 hasRelatedWork W1982412084 @default.
• W2024946537 hasRelatedWork W2091705121 @default.
• W2024946537 hasRelatedWork W2104146833 @default.
• W2024946537 hasRelatedWork W2279675031 @default.

• next