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• W2024952986 startingPage "56" @default.
• W2024952986 abstract "Sphingosine-1-phosphate (S1P), platelet activating factor (PAF) and eicosanoids are bioactive lipid mediators abundantly produced by antigen-stimulated mast cells that exert their function mostly through specific cell surface receptors. Although it has long been recognized that some of these bioactive lipids are potent regulators of allergic diseases, their exact contributions to disease pathology have been obscured by the complexity of their mode of action and the regulation of their metabolism. Indeed, the effects of such lipids are usually mediated by multiple receptor subtypes that may differ in their signaling mechanisms and functions. In addition, their actions may be elicited by cell surface receptor-independent mechanisms. Furthermore, these lipids may be converted into metabolites that exhibit different functionalities, adding another layer of complexity to their overall biological responses. In some instances, a second wave of lipid mediator synthesis by both mast cell and non-mast cell sources may occur late during inflammation, bringing about additional roles in the altered environment. New evidence also suggests that bioactive lipids in the local environment can fine-tune mast cell maturation and phenotype, and thus their responsiveness. A better understanding of the subtleties of the spatiotemporal regulation of these lipid mediators, their receptors and functions may aid in the pursuit of pharmacological applications for allergy treatments." @default.
• W2024952986 created "2016-06-24" @default.
• W2024952986 creator A5020021148 @default.
• W2024952986 creator A5042538221 @default.
• W2024952986 creator A5071300125 @default.
• W2024952986 date "2016-05-01" @default.
• W2024952986 modified "2023-09-25" @default.
• W2024952986 title "Sphingosine-1-phosphate and other lipid mediators generated by mast cells as critical players in allergy and mast cell function" @default.
• W2024952986 cites W1481141593 @default.
• W2024952986 cites W1554644961 @default.
• W2024952986 cites W1589202049 @default.
• W2024952986 cites W1590104418 @default.
• W2024952986 cites W1597248539 @default.
• W2024952986 cites W180265257 @default.
• W2024952986 cites W1860539694 @default.
• W2024952986 cites W1902070873 @default.
• W2024952986 cites W1926255205 @default.
• W2024952986 cites W1953077261 @default.
• W2024952986 cites W1963773342 @default.
• W2024952986 cites W1964682360 @default.
• W2024952986 cites W1965295681 @default.
• W2024952986 cites W1966452335 @default.
• W2024952986 cites W1967253615 @default.
• W2024952986 cites W1967802627 @default.
• W2024952986 cites W1969171973 @default.
• W2024952986 cites W1969871007 @default.
• W2024952986 cites W1974829480 @default.
• W2024952986 cites W1978707192 @default.
• W2024952986 cites W1981034102 @default.
• W2024952986 cites W1981431081 @default.
• W2024952986 cites W1982386486 @default.
• W2024952986 cites W1982965514 @default.
• W2024952986 cites W1983043199 @default.
• W2024952986 cites W1985193797 @default.
• W2024952986 cites W1989975786 @default.
• W2024952986 cites W1996605319 @default.
• W2024952986 cites W1997486939 @default.
• W2024952986 cites W1997561160 @default.
• W2024952986 cites W2003251689 @default.
• W2024952986 cites W2004148398 @default.
• W2024952986 cites W2004192317 @default.
• W2024952986 cites W2004561916 @default.
• W2024952986 cites W2005467120 @default.
• W2024952986 cites W2007281248 @default.
• W2024952986 cites W2009021880 @default.
• W2024952986 cites W2009251019 @default.
• W2024952986 cites W2009716334 @default.
• W2024952986 cites W2010923089 @default.
• W2024952986 cites W2017091970 @default.
• W2024952986 cites W2018463110 @default.
• W2024952986 cites W2019119600 @default.
• W2024952986 cites W2019209482 @default.
• W2024952986 cites W2022585439 @default.
• W2024952986 cites W2023691306 @default.
• W2024952986 cites W2024921751 @default.
• W2024952986 cites W2026086105 @default.
• W2024952986 cites W2030634089 @default.
• W2024952986 cites W2031711483 @default.
• W2024952986 cites W2033050749 @default.
• W2024952986 cites W2035023446 @default.
• W2024952986 cites W2036400427 @default.
• W2024952986 cites W2037155515 @default.
• W2024952986 cites W2038891352 @default.
• W2024952986 cites W2038960406 @default.
• W2024952986 cites W2041806010 @default.
• W2024952986 cites W2045621756 @default.
• W2024952986 cites W2047141436 @default.
• W2024952986 cites W2047607345 @default.
• W2024952986 cites W2047773927 @default.
• W2024952986 cites W2048085891 @default.
• W2024952986 cites W2050927750 @default.
• W2024952986 cites W2050976447 @default.
• W2024952986 cites W2051693683 @default.
• W2024952986 cites W2053312234 @default.
• W2024952986 cites W2055687230 @default.
• W2024952986 cites W2056772956 @default.
• W2024952986 cites W2056899647 @default.
• W2024952986 cites W2061338163 @default.
• W2024952986 cites W2062286567 @default.
• W2024952986 cites W2062581468 @default.
• W2024952986 cites W2068019570 @default.
• W2024952986 cites W2070677984 @default.
• W2024952986 cites W2074109173 @default.
• W2024952986 cites W2075931251 @default.
• W2024952986 cites W2076738925 @default.
• W2024952986 cites W2082771210 @default.
• W2024952986 cites W2084654786 @default.
• W2024952986 cites W2087584115 @default.
• W2024952986 cites W2087612399 @default.
• W2024952986 cites W2088285961 @default.
• W2024952986 cites W2090205957 @default.
• W2024952986 cites W2092056143 @default.
• W2024952986 cites W2092576605 @default.
• W2024952986 cites W2097871689 @default.
• W2024952986 cites W2098967308 @default.
• W2024952986 cites W2100117589 @default.
• W2024952986 cites W2100705331 @default.
• W2024952986 cites W2103010344 @default.

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