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- W2024961611 abstract "Calculations are presented for the determination of radiation dose delivered by internally administered radioisotopes to specific tumour sites and to critical areas in the body. Some of the variables included in these calculations are: the metabolizing function of the isotope in the various sites, the half life, the beta and gamma ray energies of the isotope, and the tumour size. From this, an expression has been obtained for the ratio of dose in the critical volume and the tumour, and the effect of the various parameters on this ratio. The derived expressions are used to calculate the relative advantage of various iodine isotopes from data on nine patients who received therapeutic doses of 131I. The calculatiosn indicate that for most patients the iodine isotopes having a higher beta to gamma ray energy ratio are more advantageous to use, as long as their half life is of the order of one day or more. It appears that 131I is probably not always the most desirable of the iodine isotopes for maximal tumour and minimal critical volume irradiation." @default.
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- W2024961611 date "1957-01-01" @default.
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- W2024961611 title "Some Physical Considerations Governing the Choice of Internally Administered Radioisotopes for Therapy" @default.
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- W2024961611 doi "https://doi.org/10.1088/0031-9155/1/3/303" @default.
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