FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2024962906> ?p ?o ?g. }

• W2024962906 endingPage "1677" @default.
• W2024962906 startingPage "1671" @default.
• W2024962906 abstract "Using a high-resolution optical trapping instrument, we directly observed the processive motions of individual Eg5 dimers over a range of external loads and ATP, ADP, and phosphate concentrations. To constrain possible models for dissociation from the microtubule, we measured Eg5 run lengths and also compared the duration of the last step of a processive run to all previous step durations. We found that the application of large longitudinal forces in either hindering or assisting directions could induce Eg5-microtubule dissociation. At a constant moderate force, maintained with a force clamp, the premature binding of ADP strongly promoted microtubule release by Eg5, whereas the addition of ATP or phosphate had little effect on dissociation. These results imply that run length is determined not only by the load, but also by the concentration and type of nucleotides present, and therefore that the biochemical cycles of the two motor domains of the Eg5 dimer are coordinated to promote processive stepping." @default.
• W2024962906 created "2016-06-24" @default.
• W2024962906 creator A5055039160 @default.
• W2024962906 creator A5085429881 @default.
• W2024962906 date "2009-09-01" @default.
• W2024962906 modified "2023-10-03" @default.
• W2024962906 title "Force and Premature Binding of ADP Can Regulate the Processivity of Individual Eg5 Dimers" @default.
• W2024962906 cites W1594344520 @default.
• W2024962906 cites W1618955965 @default.
• W2024962906 cites W1969098247 @default.
• W2024962906 cites W1978668789 @default.
• W2024962906 cites W1982003147 @default.
• W2024962906 cites W1992271499 @default.
• W2024962906 cites W1996396451 @default.
• W2024962906 cites W1998198313 @default.
• W2024962906 cites W2003537255 @default.
• W2024962906 cites W2004568111 @default.
• W2024962906 cites W2015281071 @default.
• W2024962906 cites W2020010253 @default.
• W2024962906 cites W2028383422 @default.
• W2024962906 cites W2032261838 @default.
• W2024962906 cites W2035150925 @default.
• W2024962906 cites W2036003554 @default.
• W2024962906 cites W2046320664 @default.
• W2024962906 cites W2059800534 @default.
• W2024962906 cites W2068118509 @default.
• W2024962906 cites W2078336417 @default.
• W2024962906 cites W2080111827 @default.
• W2024962906 cites W2081963355 @default.
• W2024962906 cites W2097613703 @default.
• W2024962906 cites W2142022393 @default.
• W2024962906 cites W2146314877 @default.
• W2024962906 cites W2159378744 @default.
• W2024962906 cites W4211178136 @default.
• W2024962906 doi "https://doi.org/10.1016/j.bpj.2009.07.013" @default.
• W2024962906 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2749793" @default.
• W2024962906 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19751672" @default.
• W2024962906 hasPublicationYear "2009" @default.
• W2024962906 type Work @default.
• W2024962906 sameAs 2024962906 @default.
• W2024962906 citedByCount "34" @default.
• W2024962906 countsByYear W20249629062012 @default.
• W2024962906 countsByYear W20249629062013 @default.
• W2024962906 countsByYear W20249629062014 @default.
• W2024962906 countsByYear W20249629062015 @default.
• W2024962906 countsByYear W20249629062016 @default.
• W2024962906 countsByYear W20249629062017 @default.
• W2024962906 countsByYear W20249629062018 @default.
• W2024962906 countsByYear W20249629062019 @default.
• W2024962906 countsByYear W20249629062020 @default.
• W2024962906 countsByYear W20249629062021 @default.
• W2024962906 countsByYear W20249629062023 @default.
• W2024962906 crossrefType "journal-article" @default.
• W2024962906 hasAuthorship W2024962906A5055039160 @default.
• W2024962906 hasAuthorship W2024962906A5085429881 @default.
• W2024962906 hasBestOaLocation W20249629061 @default.
• W2024962906 hasConcept C102931765 @default.
• W2024962906 hasConcept C104317684 @default.
• W2024962906 hasConcept C12554922 @default.
• W2024962906 hasConcept C131140672 @default.
• W2024962906 hasConcept C147789679 @default.
• W2024962906 hasConcept C170493617 @default.
• W2024962906 hasConcept C178790620 @default.
• W2024962906 hasConcept C185592680 @default.
• W2024962906 hasConcept C20418707 @default.
• W2024962906 hasConcept C2777132085 @default.
• W2024962906 hasConcept C2779546866 @default.
• W2024962906 hasConcept C2779564974 @default.
• W2024962906 hasConcept C512185932 @default.
• W2024962906 hasConcept C552990157 @default.
• W2024962906 hasConcept C55493867 @default.
• W2024962906 hasConcept C59006786 @default.
• W2024962906 hasConcept C73573662 @default.
• W2024962906 hasConcept C74998103 @default.
• W2024962906 hasConcept C86803240 @default.
• W2024962906 hasConcept C95444343 @default.
• W2024962906 hasConceptScore W2024962906C102931765 @default.
• W2024962906 hasConceptScore W2024962906C104317684 @default.
• W2024962906 hasConceptScore W2024962906C12554922 @default.
• W2024962906 hasConceptScore W2024962906C131140672 @default.
• W2024962906 hasConceptScore W2024962906C147789679 @default.
• W2024962906 hasConceptScore W2024962906C170493617 @default.
• W2024962906 hasConceptScore W2024962906C178790620 @default.
• W2024962906 hasConceptScore W2024962906C185592680 @default.
• W2024962906 hasConceptScore W2024962906C20418707 @default.
• W2024962906 hasConceptScore W2024962906C2777132085 @default.
• W2024962906 hasConceptScore W2024962906C2779546866 @default.
• W2024962906 hasConceptScore W2024962906C2779564974 @default.
• W2024962906 hasConceptScore W2024962906C512185932 @default.
• W2024962906 hasConceptScore W2024962906C552990157 @default.
• W2024962906 hasConceptScore W2024962906C55493867 @default.
• W2024962906 hasConceptScore W2024962906C59006786 @default.
• W2024962906 hasConceptScore W2024962906C73573662 @default.
• W2024962906 hasConceptScore W2024962906C74998103 @default.
• W2024962906 hasConceptScore W2024962906C86803240 @default.
• W2024962906 hasConceptScore W2024962906C95444343 @default.
• W2024962906 hasIssue "6" @default.
• W2024962906 hasLocation W20249629061 @default.

• next