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- W2024966734 abstract "Methods: In total, 83 patients were included in the study. All patients received a CFF analysis before, 30, 60, 90 and 120 min after the endoscopy. CFF results were correlated to sedation methods. Differences in the CFF between groups and within groups were tested by non-parametric Mann–Whitney U or paired t-tests comparisons as appropriate. Results: Overall, 33.7% of patients received no sedation, 26.5% were sedated with propofol (P) alone, and 38.6% of patients received a combination of propofol with midazolam (P/M). While in the control group no changes in CFF results were detected, patients with sedation experienced a clear drop in CFF results at 30 min. This drop was more pronounced in patients P/M-sedation as compared to P-mono sedation (30 min CFF: 37.6 Hz vs. 42.2 Hz). In addition the effect of sedation was detectable for >120min in P/M sedated patients, while CFF results in patients with P-mono sedation recovered to baseline values after 60min. Discussion/Conclusion: Our study clearly shows that the use of CFF assessment may be beyond testing for hepatic encephalopathy. We here show that the combination of propofol with midazolam leads to long lasting effects on CFF, which may affect driving capability, whereas sedation with propofol wares off within one hour. CFF analysis may be an easy to use tool to asses driving ability in this setting." @default.
- W2024966734 created "2016-06-24" @default.
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- W2024966734 date "2013-04-01" @default.
- W2024966734 modified "2023-10-16" @default.
- W2024966734 title "201 LONG-TERM EFFECT OF PROPRANOLOL ON PORTAL HYPERTENSION IN PATIENTS WITH CIRRHOSIS: A SINGLE CENTRE PROSPECTIVE EXPERIENCE" @default.
- W2024966734 doi "https://doi.org/10.1016/s0168-8278(13)60203-2" @default.
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