Matches in SemOpenAlex for { <https://semopenalex.org/work/W2024971778> ?p ?o ?g. }
- W2024971778 endingPage "250" @default.
- W2024971778 startingPage "240" @default.
- W2024971778 abstract "Iron-deficiency anemia is common in patients with heart failure (HF), but the optimum diagnostic tests to detect iron deficiency and the treatment options to replete iron have not been fully characterized. Recent studies in patients with HF indicate that intravenous iron can rapidly replenish iron stores in patients having iron-deficiency anemia, with resultant increased hemoglobin levels and improved functional capacity. Preliminary data from a subgroup analysis also suggest that supplemental intravenous iron therapy can improve functional capacity even in those subjects without anemia. The mechanisms responsible for this observation are not fully characterized, but may be related to beneficial effects of iron supplementation on mitochondrial respiration in skeletal muscle. The long-term safety of using intravenous iron supplementation in HF populations is not known. Iron is a known pro-oxidant factor that can inhibit nitric oxide signaling and irreversibly injury cells. Increased iron stores are associated with vascular endothelial dysfunction and increased risk of coronary heart disease events. Additional clinical trials are needed to more fully characterize the therapeutic potential and safety of intravenous iron in HF patients." @default.
- W2024971778 created "2016-06-24" @default.
- W2024971778 creator A5010862737 @default.
- W2024971778 creator A5063740588 @default.
- W2024971778 date "2010-09-01" @default.
- W2024971778 modified "2023-09-24" @default.
- W2024971778 title "Treatment of Anemia in Heart Failure" @default.
- W2024971778 cites W1506934700 @default.
- W2024971778 cites W1516636175 @default.
- W2024971778 cites W1551604012 @default.
- W2024971778 cites W162181629 @default.
- W2024971778 cites W1634979164 @default.
- W2024971778 cites W1638845934 @default.
- W2024971778 cites W17798182 @default.
- W2024971778 cites W1914307777 @default.
- W2024971778 cites W1921779008 @default.
- W2024971778 cites W1929345885 @default.
- W2024971778 cites W1933201213 @default.
- W2024971778 cites W1971128957 @default.
- W2024971778 cites W1971584572 @default.
- W2024971778 cites W1973691249 @default.
- W2024971778 cites W1975036384 @default.
- W2024971778 cites W1976555160 @default.
- W2024971778 cites W1977731938 @default.
- W2024971778 cites W1980042430 @default.
- W2024971778 cites W1980459953 @default.
- W2024971778 cites W1981922048 @default.
- W2024971778 cites W1983523884 @default.
- W2024971778 cites W1983986018 @default.
- W2024971778 cites W1984148894 @default.
- W2024971778 cites W1984217618 @default.
- W2024971778 cites W1988375247 @default.
- W2024971778 cites W1990618897 @default.
- W2024971778 cites W1991372112 @default.
- W2024971778 cites W1993318146 @default.
- W2024971778 cites W1994033703 @default.
- W2024971778 cites W1995162700 @default.
- W2024971778 cites W1995282389 @default.
- W2024971778 cites W1997754364 @default.
- W2024971778 cites W2001806476 @default.
- W2024971778 cites W2002055621 @default.
- W2024971778 cites W2004285067 @default.
- W2024971778 cites W2006358233 @default.
- W2024971778 cites W2006984835 @default.
- W2024971778 cites W2009281149 @default.
- W2024971778 cites W2012920582 @default.
- W2024971778 cites W2014520319 @default.
- W2024971778 cites W2015738659 @default.
- W2024971778 cites W2018769683 @default.
- W2024971778 cites W2019317728 @default.
- W2024971778 cites W2022942610 @default.
- W2024971778 cites W2024074211 @default.
- W2024971778 cites W2024633506 @default.
- W2024971778 cites W2025403494 @default.
- W2024971778 cites W2029753366 @default.
- W2024971778 cites W2031739105 @default.
- W2024971778 cites W2043185568 @default.
- W2024971778 cites W2048494288 @default.
- W2024971778 cites W2056325568 @default.
- W2024971778 cites W2056823828 @default.
- W2024971778 cites W2060348573 @default.
- W2024971778 cites W2065303599 @default.
- W2024971778 cites W2065629260 @default.
- W2024971778 cites W2066929242 @default.
- W2024971778 cites W2067052960 @default.
- W2024971778 cites W2067573387 @default.
- W2024971778 cites W2068877594 @default.
- W2024971778 cites W2069130738 @default.
- W2024971778 cites W2072738759 @default.
- W2024971778 cites W2072848251 @default.
- W2024971778 cites W2075532969 @default.
- W2024971778 cites W2081098766 @default.
- W2024971778 cites W2083007412 @default.
- W2024971778 cites W2091271949 @default.
- W2024971778 cites W2091543383 @default.
- W2024971778 cites W2092052199 @default.
- W2024971778 cites W2092619576 @default.
- W2024971778 cites W2094466107 @default.
- W2024971778 cites W2096750760 @default.
- W2024971778 cites W2097014671 @default.
- W2024971778 cites W2102538853 @default.
- W2024971778 cites W2103730730 @default.
- W2024971778 cites W2105370709 @default.
- W2024971778 cites W2105487937 @default.
- W2024971778 cites W2106989655 @default.
- W2024971778 cites W2111498248 @default.
- W2024971778 cites W2113083124 @default.
- W2024971778 cites W2113264115 @default.
- W2024971778 cites W2114015514 @default.
- W2024971778 cites W2116073940 @default.
- W2024971778 cites W2119007591 @default.
- W2024971778 cites W2122095496 @default.
- W2024971778 cites W2122529949 @default.
- W2024971778 cites W2122537544 @default.
- W2024971778 cites W2123200029 @default.
- W2024971778 cites W2126989415 @default.
- W2024971778 cites W2133886253 @default.
- W2024971778 cites W2136699926 @default.