Matches in SemOpenAlex for { <https://semopenalex.org/work/W2024992661> ?p ?o ?g. }
Showing items 1 to 94 of
94
with 100 items per page.
- W2024992661 endingPage "343" @default.
- W2024992661 startingPage "337" @default.
- W2024992661 abstract "Previous work indicated that the light chains of a monotypic immunoglobulins G2-K and M-K from a single patient (Ti1) are identical. Our present data show that the monotypic immunoglobulins G and M share idiotypic determinants not present in their isolated light chains or in any of a large number of other immunoglobulins tested, and that amino acid sequences of the first 27 residues from the NH(2)-terminal end of the gamma- and mu-chains are identical. These results support the hypothesis that at least two genes control the synthesis of each heavy and light chain and suggest that the monotypic immunoglobulin G and monotypic immunoglobulin M of this patient share three of the four genes involved. It is proposed that, during normal immunoglobulin synthesis, different cells of a single clone synthesize immunoglobulins M and G, and that the light chains and the variable segments of the heavy chains of the proteins of the two classes are identical within the clone. A genetic switching mechanism is suggested." @default.
- W2024992661 created "2016-06-24" @default.
- W2024992661 creator A5010695214 @default.
- W2024992661 creator A5025097601 @default.
- W2024992661 creator A5026864455 @default.
- W2024992661 creator A5031615257 @default.
- W2024992661 creator A5041745642 @default.
- W2024992661 date "1970-06-01" @default.
- W2024992661 modified "2023-09-26" @default.
- W2024992661 title "Evidence for Control of Synthesis of the Variable Regions of the Heavy Chains of Immunoglobulins G and M by the Same Gene" @default.
- W2024992661 cites W144754746 @default.
- W2024992661 cites W1497745573 @default.
- W2024992661 cites W1558173094 @default.
- W2024992661 cites W1566429952 @default.
- W2024992661 cites W1786523947 @default.
- W2024992661 cites W1969118181 @default.
- W2024992661 cites W1988348862 @default.
- W2024992661 cites W1989170328 @default.
- W2024992661 cites W2004060933 @default.
- W2024992661 cites W2030903875 @default.
- W2024992661 cites W2038681434 @default.
- W2024992661 cites W2040462944 @default.
- W2024992661 cites W2040613162 @default.
- W2024992661 cites W2041116516 @default.
- W2024992661 cites W2053228535 @default.
- W2024992661 cites W2062523329 @default.
- W2024992661 cites W2085474307 @default.
- W2024992661 cites W2085649019 @default.
- W2024992661 cites W2135154448 @default.
- W2024992661 cites W2135579916 @default.
- W2024992661 cites W2158479512 @default.
- W2024992661 cites W2258043690 @default.
- W2024992661 cites W2398849845 @default.
- W2024992661 doi "https://doi.org/10.1073/pnas.66.2.337" @default.
- W2024992661 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/283049" @default.
- W2024992661 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/4988920" @default.
- W2024992661 hasPublicationYear "1970" @default.
- W2024992661 type Work @default.
- W2024992661 sameAs 2024992661 @default.
- W2024992661 citedByCount "166" @default.
- W2024992661 countsByYear W20249926612014 @default.
- W2024992661 countsByYear W20249926612016 @default.
- W2024992661 countsByYear W20249926612019 @default.
- W2024992661 crossrefType "journal-article" @default.
- W2024992661 hasAuthorship W2024992661A5010695214 @default.
- W2024992661 hasAuthorship W2024992661A5025097601 @default.
- W2024992661 hasAuthorship W2024992661A5026864455 @default.
- W2024992661 hasAuthorship W2024992661A5031615257 @default.
- W2024992661 hasAuthorship W2024992661A5041745642 @default.
- W2024992661 hasBestOaLocation W20249926611 @default.
- W2024992661 hasConcept C104317684 @default.
- W2024992661 hasConcept C153911025 @default.
- W2024992661 hasConcept C159654299 @default.
- W2024992661 hasConcept C185592680 @default.
- W2024992661 hasConcept C36394416 @default.
- W2024992661 hasConcept C515207424 @default.
- W2024992661 hasConcept C54355233 @default.
- W2024992661 hasConcept C81089528 @default.
- W2024992661 hasConcept C86803240 @default.
- W2024992661 hasConcept C96007430 @default.
- W2024992661 hasConceptScore W2024992661C104317684 @default.
- W2024992661 hasConceptScore W2024992661C153911025 @default.
- W2024992661 hasConceptScore W2024992661C159654299 @default.
- W2024992661 hasConceptScore W2024992661C185592680 @default.
- W2024992661 hasConceptScore W2024992661C36394416 @default.
- W2024992661 hasConceptScore W2024992661C515207424 @default.
- W2024992661 hasConceptScore W2024992661C54355233 @default.
- W2024992661 hasConceptScore W2024992661C81089528 @default.
- W2024992661 hasConceptScore W2024992661C86803240 @default.
- W2024992661 hasConceptScore W2024992661C96007430 @default.
- W2024992661 hasIssue "2" @default.
- W2024992661 hasLocation W20249926611 @default.
- W2024992661 hasLocation W20249926612 @default.
- W2024992661 hasLocation W20249926613 @default.
- W2024992661 hasLocation W20249926614 @default.
- W2024992661 hasOpenAccess W2024992661 @default.
- W2024992661 hasPrimaryLocation W20249926611 @default.
- W2024992661 hasRelatedWork W1658725198 @default.
- W2024992661 hasRelatedWork W1997644086 @default.
- W2024992661 hasRelatedWork W2023401925 @default.
- W2024992661 hasRelatedWork W2079479943 @default.
- W2024992661 hasRelatedWork W2091394389 @default.
- W2024992661 hasRelatedWork W2117287173 @default.
- W2024992661 hasRelatedWork W2142734193 @default.
- W2024992661 hasRelatedWork W2356773502 @default.
- W2024992661 hasRelatedWork W2371667595 @default.
- W2024992661 hasRelatedWork W56988916 @default.
- W2024992661 hasVolume "66" @default.
- W2024992661 isParatext "false" @default.
- W2024992661 isRetracted "false" @default.
- W2024992661 magId "2024992661" @default.
- W2024992661 workType "article" @default.