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- W2025122173 abstract "A 26-year-old woman had a chronic vesiculopustular and ulcerating skin disease associated with fever and arthritis. Cutaneous biopsy specimens showed an extensive infiltration of the dermis and epidermis by neutrophils. Direct immunofluorescence (IF) revealed linear subcorneal IgA deposits. Indirect IF showed IgA antibodies reactive with the subcorneal zone of normal epidermis. The disease responded to dapsone therapy. The association between neutrophilic dermatoses, including pyoderma gangrenosum, subcorneal pustular dermatosis, and related entities, and IgA involvement, either IgA gammopathies and/or intraepidermal IgA deposits, is emphasized. Intraepidermal IgA deposits are possibly involved in the pathogenesis of our patient's condition and of other cases of unusual neutrophilic dermatoses." @default.
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- W2025122173 date "1987-06-01" @default.
- W2025122173 modified "2023-09-30" @default.
- W2025122173 title "Atypical Neutrophilic Dermatosis With Subcorneal IgA Deposits" @default.
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- W2025122173 doi "https://doi.org/10.1001/archderm.1987.01660300112023" @default.
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