FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2025133748> ?p ?o ?g. }

• W2025133748 endingPage "138" @default.
• W2025133748 startingPage "125" @default.
• W2025133748 abstract "Differentiation of human promyelocytic leukemic HL-60 cells with 1,25-dihydroxyvitamin D3 (D3) results in macrophages which exhibit specific and saturable receptor-mediated processing of both native and modified low density lipoprotein (LDL). Analysis of binding kinetics demonstrated that macrophages bind LDL and acetyl-LDL with similar affinities, yet possess significantly different numbers of receptors (55 ± 6 × 103 LDL receptors/cell vs. 79 ± 7 × 103 acetyl-LDL receptors/cell). D3-induced HL-60 macrophages challenged with LDL or acetyl-LDL exhibited suppression of HMG-CoA reductase activity as well as a significant induction in the incorporation of [14C]oleate into cholesteryl ester compared with macrophages incubated with lipoprotein depleted serum. Maximum increases in ACAT activity were obtained in macrophages incubated with 25-hydroxycholesterol plus LDL or acetyl-LDL. The increase in ACAT activity in macrophages challenged with acetyl-LDL paralleled the increase in cellular cholesterol content and the increase of oil red O lipid stainable material, imparting the macrophages with a foamy appearance. The data indicate that D3-induced HL-60 macrophages are a useful model for the study of lipoprotein -macrophage interactions as related to foam cell development and atherogenesis." @default.
• W2025133748 created "2016-06-24" @default.
• W2025133748 creator A5011486852 @default.
• W2025133748 creator A5073141504 @default.
• W2025133748 creator A5085549448 @default.
• W2025133748 date "1995-09-01" @default.
• W2025133748 modified "2023-09-24" @default.
• W2025133748 title "1,25-Dihydroxyvitamin D3-induced HL-60 macrophages: regulation of cholesterol and LDL metabolism" @default.
• W2025133748 cites W1522459970 @default.
• W2025133748 cites W1551929711 @default.
• W2025133748 cites W1584098714 @default.
• W2025133748 cites W1940775645 @default.
• W2025133748 cites W1961766522 @default.
• W2025133748 cites W1974012901 @default.
• W2025133748 cites W1983136273 @default.
• W2025133748 cites W1988003237 @default.
• W2025133748 cites W1995571665 @default.
• W2025133748 cites W2001977943 @default.
• W2025133748 cites W2009693687 @default.
• W2025133748 cites W2018108516 @default.
• W2025133748 cites W2023574502 @default.
• W2025133748 cites W2024352183 @default.
• W2025133748 cites W2029519920 @default.
• W2025133748 cites W2031423487 @default.
• W2025133748 cites W2044372455 @default.
• W2025133748 cites W2056525574 @default.
• W2025133748 cites W2061558567 @default.
• W2025133748 cites W2079619920 @default.
• W2025133748 cites W2081133886 @default.
• W2025133748 cites W2086462010 @default.
• W2025133748 cites W2125123943 @default.
• W2025133748 cites W2135503869 @default.
• W2025133748 cites W2139405057 @default.
• W2025133748 cites W2153716751 @default.
• W2025133748 cites W2162458714 @default.
• W2025133748 cites W2184891169 @default.
• W2025133748 cites W2410526045 @default.
• W2025133748 doi "https://doi.org/10.1016/0021-9150(95)05569-i" @default.
• W2025133748 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8546749" @default.
• W2025133748 hasPublicationYear "1995" @default.
• W2025133748 type Work @default.
• W2025133748 sameAs 2025133748 @default.
• W2025133748 citedByCount "16" @default.
• W2025133748 countsByYear W20251337482014 @default.
• W2025133748 countsByYear W20251337482016 @default.
• W2025133748 countsByYear W20251337482017 @default.
• W2025133748 countsByYear W20251337482018 @default.
• W2025133748 countsByYear W20251337482021 @default.
• W2025133748 countsByYear W20251337482023 @default.
• W2025133748 crossrefType "journal-article" @default.
• W2025133748 hasAuthorship W2025133748A5011486852 @default.
• W2025133748 hasAuthorship W2025133748A5073141504 @default.
• W2025133748 hasAuthorship W2025133748A5085549448 @default.
• W2025133748 hasConcept C126322002 @default.
• W2025133748 hasConcept C134018914 @default.
• W2025133748 hasConcept C134651460 @default.
• W2025133748 hasConcept C1491633281 @default.
• W2025133748 hasConcept C170493617 @default.
• W2025133748 hasConcept C181199279 @default.
• W2025133748 hasConcept C185592680 @default.
• W2025133748 hasConcept C202751555 @default.
• W2025133748 hasConcept C2776448209 @default.
• W2025133748 hasConcept C2777895019 @default.
• W2025133748 hasConcept C2778163477 @default.
• W2025133748 hasConcept C2779244956 @default.
• W2025133748 hasConcept C2779620165 @default.
• W2025133748 hasConcept C2780072125 @default.
• W2025133748 hasConcept C43554185 @default.
• W2025133748 hasConcept C55493867 @default.
• W2025133748 hasConcept C62231903 @default.
• W2025133748 hasConcept C71924100 @default.
• W2025133748 hasConcept C86803240 @default.
• W2025133748 hasConceptScore W2025133748C126322002 @default.
• W2025133748 hasConceptScore W2025133748C134018914 @default.
• W2025133748 hasConceptScore W2025133748C134651460 @default.
• W2025133748 hasConceptScore W2025133748C1491633281 @default.
• W2025133748 hasConceptScore W2025133748C170493617 @default.
• W2025133748 hasConceptScore W2025133748C181199279 @default.
• W2025133748 hasConceptScore W2025133748C185592680 @default.
• W2025133748 hasConceptScore W2025133748C202751555 @default.
• W2025133748 hasConceptScore W2025133748C2776448209 @default.
• W2025133748 hasConceptScore W2025133748C2777895019 @default.
• W2025133748 hasConceptScore W2025133748C2778163477 @default.
• W2025133748 hasConceptScore W2025133748C2779244956 @default.
• W2025133748 hasConceptScore W2025133748C2779620165 @default.
• W2025133748 hasConceptScore W2025133748C2780072125 @default.
• W2025133748 hasConceptScore W2025133748C43554185 @default.
• W2025133748 hasConceptScore W2025133748C55493867 @default.
• W2025133748 hasConceptScore W2025133748C62231903 @default.
• W2025133748 hasConceptScore W2025133748C71924100 @default.
• W2025133748 hasConceptScore W2025133748C86803240 @default.
• W2025133748 hasIssue "1" @default.
• W2025133748 hasLocation W20251337481 @default.
• W2025133748 hasLocation W20251337482 @default.
• W2025133748 hasOpenAccess W2025133748 @default.
• W2025133748 hasPrimaryLocation W20251337481 @default.
• W2025133748 hasRelatedWork W1483555478 @default.
• W2025133748 hasRelatedWork W1965824532 @default.

• next