Matches in SemOpenAlex for { <https://semopenalex.org/work/W2025149767> ?p ?o ?g. }
- W2025149767 endingPage "3658" @default.
- W2025149767 startingPage "3647" @default.
- W2025149767 abstract "The binding of alkyl polyglucoside surfactants to the integral membrane protein bacteriorhodopsin (BR) and the formation of protein-surfactant complexes are investigated by sedimentation equilibrium via analytical ultracentrifugation and by small-angle neutron scattering (SANS). Contrast variation techniques in SANS enable measurement of the composition of the protein-surfactant complexes and determination of the thickness of the surfactant shell bound to the protein. The results indicate that alkyl polyglucosides can bind to BR as single surfactant layers or as a thicker shell. The thickness of the surfactant shell increases with increasing surfactant tail length, and it is generally unrelated to the aggregation number of the micelles even for a small and predominantly hydrophobic membrane protein such as BR. The aggregation numbers determined by sedimentation equilibrium methods match those measured by SANS, which also allows reconstruction of the shape of the protein-detergent complex. When the surfactant is present as a single layer, the BR loses activity, as measured by absorption spectroscopy, more quickly than it does when the surfactant forms a thicker shell." @default.
- W2025149767 created "2016-06-24" @default.
- W2025149767 creator A5035543889 @default.
- W2025149767 creator A5066262156 @default.
- W2025149767 creator A5089483150 @default.
- W2025149767 date "2008-05-01" @default.
- W2025149767 modified "2023-09-28" @default.
- W2025149767 title "Binding of Alkyl Polyglucoside Surfactants to Bacteriorhodopsin and its Relation to Protein Stability" @default.
- W2025149767 cites W1135361602 @default.
- W2025149767 cites W1539854477 @default.
- W2025149767 cites W1568485433 @default.
- W2025149767 cites W1578237028 @default.
- W2025149767 cites W1590125256 @default.
- W2025149767 cites W1603492764 @default.
- W2025149767 cites W1633800597 @default.
- W2025149767 cites W1964918473 @default.
- W2025149767 cites W1970950588 @default.
- W2025149767 cites W1973956782 @default.
- W2025149767 cites W1977165929 @default.
- W2025149767 cites W1977569471 @default.
- W2025149767 cites W1980600205 @default.
- W2025149767 cites W1981095163 @default.
- W2025149767 cites W1989952650 @default.
- W2025149767 cites W1990849016 @default.
- W2025149767 cites W1991557711 @default.
- W2025149767 cites W1999167338 @default.
- W2025149767 cites W2002996832 @default.
- W2025149767 cites W2024720882 @default.
- W2025149767 cites W2026522058 @default.
- W2025149767 cites W2029820720 @default.
- W2025149767 cites W2030360492 @default.
- W2025149767 cites W2031089297 @default.
- W2025149767 cites W2036116716 @default.
- W2025149767 cites W2036274744 @default.
- W2025149767 cites W2039485889 @default.
- W2025149767 cites W2040100125 @default.
- W2025149767 cites W2048695489 @default.
- W2025149767 cites W2049121705 @default.
- W2025149767 cites W2052419681 @default.
- W2025149767 cites W2056852427 @default.
- W2025149767 cites W2060741615 @default.
- W2025149767 cites W2064497637 @default.
- W2025149767 cites W2072546470 @default.
- W2025149767 cites W2079946015 @default.
- W2025149767 cites W2080281812 @default.
- W2025149767 cites W2082203480 @default.
- W2025149767 cites W2083610397 @default.
- W2025149767 cites W2083730441 @default.
- W2025149767 cites W2090966049 @default.
- W2025149767 cites W2105621770 @default.
- W2025149767 cites W2115357061 @default.
- W2025149767 cites W2130513806 @default.
- W2025149767 cites W2133308354 @default.
- W2025149767 cites W2136470366 @default.
- W2025149767 cites W2137361193 @default.
- W2025149767 cites W2170408275 @default.
- W2025149767 cites W2241011136 @default.
- W2025149767 cites W2319763409 @default.
- W2025149767 cites W2743625347 @default.
- W2025149767 cites W4213345487 @default.
- W2025149767 cites W4250873843 @default.
- W2025149767 doi "https://doi.org/10.1529/biophysj.107.113258" @default.
- W2025149767 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2292374" @default.
- W2025149767 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18234822" @default.
- W2025149767 hasPublicationYear "2008" @default.
- W2025149767 type Work @default.
- W2025149767 sameAs 2025149767 @default.
- W2025149767 citedByCount "29" @default.
- W2025149767 countsByYear W20251497672012 @default.
- W2025149767 countsByYear W20251497672013 @default.
- W2025149767 countsByYear W20251497672014 @default.
- W2025149767 countsByYear W20251497672015 @default.
- W2025149767 countsByYear W20251497672016 @default.
- W2025149767 countsByYear W20251497672018 @default.
- W2025149767 countsByYear W20251497672019 @default.
- W2025149767 countsByYear W20251497672020 @default.
- W2025149767 countsByYear W20251497672022 @default.
- W2025149767 countsByYear W20251497672023 @default.
- W2025149767 crossrefType "journal-article" @default.
- W2025149767 hasAuthorship W2025149767A5035543889 @default.
- W2025149767 hasAuthorship W2025149767A5066262156 @default.
- W2025149767 hasAuthorship W2025149767A5089483150 @default.
- W2025149767 hasBestOaLocation W20251497671 @default.
- W2025149767 hasConcept C104015590 @default.
- W2025149767 hasConcept C11268172 @default.
- W2025149767 hasConcept C120665830 @default.
- W2025149767 hasConcept C121332964 @default.
- W2025149767 hasConcept C127413603 @default.
- W2025149767 hasConcept C132841051 @default.
- W2025149767 hasConcept C167092891 @default.
- W2025149767 hasConcept C178790620 @default.
- W2025149767 hasConcept C184651966 @default.
- W2025149767 hasConcept C185592680 @default.
- W2025149767 hasConcept C189542057 @default.
- W2025149767 hasConcept C191486275 @default.
- W2025149767 hasConcept C2780263894 @default.
- W2025149767 hasConcept C41625074 @default.
- W2025149767 hasConcept C42360764 @default.