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• W2025153527 abstract "Occupational and environmental exposure to grain dust can cause a spectrum of clinical syndromes, including asthma, acute and chronic changes in airway reactivity, grain fever, bronchitis, and progressive irreversible airflow obstruction. 1 Chan-Yeung M Enarson DA Kenney SM The impact of grain dust on respiratory health.. Am Rev Respir Dis. 1992; 145: 476-487 Crossref PubMed Google Scholar In North America alone, more than 5 million agricultural workers are exposed to grain dust each year. 1 Chan-Yeung M Enarson DA Kenney SM The impact of grain dust on respiratory health.. Am Rev Respir Dis. 1992; 145: 476-487 Crossref PubMed Google Scholar , 2 Carey P Hutchson M Broder I et al. Grain elevator workers show work-related pulmonary function changes and dose-effect relationships with dust exposure.. Br J Ind Med. 1982; 39: 330-337 Google Scholar , 3 Chan-Yeung M Schulzer M MacLean L et al. Epidemiologic health survey of grain elevator workers in British Columbia.. Am Rev Respir Dis. 1980; 121: 329-338 PubMed Google Scholar , 4 Do Pico GA Reddan W Anderson S et al. Acute effects of grain dust exposure during a work shift.. Am Rev Respir Dis. 1983; 128: 399-404 Crossref Scopus (72) Google Scholar Among grain handlers, the prevalence of work-shift changes in FEV1 (≥10% decline) varies between 3.9 and 11%. 2 Carey P Hutchson M Broder I et al. Grain elevator workers show work-related pulmonary function changes and dose-effect relationships with dust exposure.. Br J Ind Med. 1982; 39: 330-337 Google Scholar , 3 Chan-Yeung M Schulzer M MacLean L et al. Epidemiologic health survey of grain elevator workers in British Columbia.. Am Rev Respir Dis. 1980; 121: 329-338 PubMed Google Scholar , 4 Do Pico GA Reddan W Anderson S et al. Acute effects of grain dust exposure during a work shift.. Am Rev Respir Dis. 1983; 128: 399-404 Crossref Scopus (72) Google Scholar Grain fever, an acute illness consisting of fevers, chills, headache, myalgias, chest tightness, dyspnea, and a transient decline in airflow, has been reported in up to 25% of grain workers. 5 Becklake MR Jodoin G Lefort L et al. A respiratory health study of grain handlers in St. Lawrence River ports. in: Dosman JA Cotton DJ Occupational pulmonary disease: focus on grain dust and health. Academic Press, New York1980: 239-251 Google Scholar , 6 Do Pico GA Reddan W Flaherty D et al. Respiratory abnormalities among grain handlers.. Am Rev Respir Dis. 1977; 115: 915-927 PubMed Google Scholar , 7 Manfreda J Holford-Strevens V Cheang M et al. Acute symptoms following exposure to grain dust in farming.. Environ Health Perspect. 1986; 66: 73-80 Crossref PubMed Scopus (28) Google Scholar Grain dust exposure causes seasonal decrements in airflow 8 James AL Zimmerman MJ Ee H et al. Exposure to grain dust and changes in lung function.. Br J Ind Med. 1990; 47: 466-472 PubMed Google Scholar , 9 James AL Cookson WOCM Buters G et al. Symptoms and longitudinal changes in lung function in young seasonal grain handlers.. Br J Ind Med. 1986; 43: 587-591 PubMed Google Scholar , 10 McCarthy PE Cockcroft AE McDermott M Lung function after exposure to barley dust.. Br J Ind Med. 1985; 42: 106-110 Google Scholar and an accelerated longitudinal decline in FEV1. 11 McDuffie HH Pahwa P Dosman JA Respiratory health status of 3,098 Canadian grain workers studied longitudinally.. Am J Ind Med. 1991; 20: 753-762 Crossref PubMed Scopus (20) Google Scholar , 12 Chan-Yeung M Schulzer M MacLean L et al. A follow-up study of the grain elevator workers in the port of Vancouver.. Arch Environ Health. 1981; 36: 75-81 Crossref PubMed Scopus (64) Google Scholar , 13 Tabona M Chan-Yeung M Enarson D et al. Host factors affecting longitudinal decline in lung spirometry among grain elevator workers.. Chest. 1984; 85: 782-786 Crossref PubMed Scopus (91) Google Scholar , 14 Huy T Schipper KD Chan-Yeung M et al. Grain dust and lung function.. Am Rev Respir Dis. 1991; 144: 1314-1321 Crossref PubMed Scopus (84) Google Scholar Chronic bronchitis occurs in a high prevalence (23 to 37%) of grain handlers. 6 Do Pico GA Reddan W Flaherty D et al. Respiratory abnormalities among grain handlers.. Am Rev Respir Dis. 1977; 115: 915-927 PubMed Google Scholar , 11 McDuffie HH Pahwa P Dosman JA Respiratory health status of 3,098 Canadian grain workers studied longitudinally.. Am J Ind Med. 1991; 20: 753-762 Crossref PubMed Scopus (20) Google Scholar , 14 Huy T Schipper KD Chan-Yeung M et al. Grain dust and lung function.. Am Rev Respir Dis. 1991; 144: 1314-1321 Crossref PubMed Scopus (84) Google Scholar , 15 Dosman JA Cotton DJ Graham BL et al. Chronic bronchitis and decreased forced expiratory flow rates in lifetime nonsmoking grain workers.. Am Rev Respir Dis. 1980; 121: 11-16 PubMed Google Scholar The effect of cigarette smoking appears to be additive; 12 Chan-Yeung M Schulzer M MacLean L et al. A follow-up study of the grain elevator workers in the port of Vancouver.. Arch Environ Health. 1981; 36: 75-81 Crossref PubMed Scopus (64) Google Scholar , 16 Cotton DJ Graham BL Li KYR et al. Effects of grain dust exposure and smoking on respiratory symptoms and lung function.. J Occup Med. 1983; 25: 131-141 PubMed Google Scholar however, nonsmokers also develop grain dust-induced airway disease. 15 Dosman JA Cotton DJ Graham BL et al. Chronic bronchitis and decreased forced expiratory flow rates in lifetime nonsmoking grain workers.. Am Rev Respir Dis. 1980; 121: 11-16 PubMed Google Scholar , 17 Gerrard JW Mink J Cheung SC et al. Nonsmoking grain handlers in Saskatchewan: airways reactivity and allergy status.. J Occup Med. 1979; 21: 342-346 PubMed Google Scholar , 18 Mink JT Gerrard JW Cockcroft DW et al. Increased bronchial reactivity to inhaled histamine in nonsmoking grain workers with normal lung function.. Chest. 1980; 77: 28-31 Crossref PubMed Scopus (42) Google Scholar Moreover, short-term changes in airflow across either the work shift or work week are consistently associated with accelerated declines in lung function, 9 James AL Cookson WOCM Buters G et al. Symptoms and longitudinal changes in lung function in young seasonal grain handlers.. Br J Ind Med. 1986; 43: 587-591 PubMed Google Scholar , 12 Chan-Yeung M Schulzer M MacLean L et al. A follow-up study of the grain elevator workers in the port of Vancouver.. Arch Environ Health. 1981; 36: 75-81 Crossref PubMed Scopus (64) Google Scholar , 13 Tabona M Chan-Yeung M Enarson D et al. Host factors affecting longitudinal decline in lung spirometry among grain elevator workers.. Chest. 1984; 85: 782-786 Crossref PubMed Scopus (91) Google Scholar and long-term occupational exposure to grain dust is associated with impaired lung function even among retired grain workers. 19 Kennedy SM Dimich-Ward H Desjardins A et al. Respiratory health among retired grain elevator workers.. Am J Respir Crit Care Med. 1994; 150: 59-65 Crossref PubMed Scopus (25) Google Scholar" @default.
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• W2025153527 title "Grain Dust, Endotoxin, and Airflow Obstruction" @default.
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