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• W2025201211 startingPage "1625" @default.
• W2025201211 abstract "To evaluate the hepatic regenerative response in patients with alcoholic liver disease, sera from 263 patients with severe alcoholic hepatitis and/or cirrhosis were analyzed for hepatocyte growth factor (HGF) and α-fetoprotein (AFP). HGF concentration was elevated above healthy controls in 95% of the patients (median level = 2.4 ng/ml), whereas AFP tended to be depressed below controls (median level = 4.1 ng/ml). Correlations with parameters of liver injury (i.e., ascites, encephalopathy, AST bilirubin, and protime) all showed a more significant correlation with HGF concentrations than those of AFP. Patients with HGF levels below the mean (4 ng/ml) exhibited significantly better survival (median survival = 35 months vs. 8.5 months for those with HGF ≥4 ng/ml; p= 0.007). Serum HGF levels were associated with various specific histologic features of alcoholic hepatitis that included, but were not exclusively related to, necrosis." @default.
• W2025201211 created "2016-06-24" @default.
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• W2025201211 date "1996-12-01" @default.
• W2025201211 modified "2023-09-27" @default.
• W2025201211 title "Human Hepatocyte Growth Factor in Alcoholic Liver Disease: A Comparison with Change in α-Fetoprotein" @default.
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• W2025201211 doi "https://doi.org/10.1111/j.1530-0277.1996.tb01708.x" @default.
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