Matches in SemOpenAlex for { <https://semopenalex.org/work/W2025221802> ?p ?o ?g. }
- W2025221802 endingPage "1420" @default.
- W2025221802 startingPage "1413" @default.
- W2025221802 abstract "Amyloid fibres are proteinaceous aggregates associated with several human diseases, including Alzheimer's, Huntington's and Creutzfeldt Jakob's. Disease-associated amyloid formation is the result of proteins that misfold and aggregate into beta sheet-rich fibre polymers. Cellular toxicity is readily associated with amyloidogenesis, although the molecular mechanism of toxicity remains unknown. Recently, a new class of 'functional' amyloid fibres was discovered that demonstrates that amyloids can be utilized as a productive part of cellular biology. These functional amyloids will provide unique insights into how amyloid formation can be controlled and made less cytotoxic. Bacteria produce some of the best-characterized functional amyloids, including a surface amyloid fibre called curli. Assembled by enteric bacteria, curli fibres mediate attachment to surfaces and host tissues. Some bacterial amyloids, like harpins and microcinE492, have exploited amyloid toxicity in a directed and functional manner. Here, we review and discuss the functional amyloids assembled by bacteria. Special emphasis will be paid to the biology of functional amyloid synthesis and the connections between bacterial physiology and pathology." @default.
- W2025221802 created "2016-06-24" @default.
- W2025221802 creator A5005219196 @default.
- W2025221802 creator A5024846442 @default.
- W2025221802 date "2008-07-01" @default.
- W2025221802 modified "2023-10-13" @default.
- W2025221802 title "Polymerizing the fibre between bacteria and host cells: the biogenesis of functional amyloid fibres" @default.
- W2025221802 cites W1489521232 @default.
- W2025221802 cites W1542452066 @default.
- W2025221802 cites W1553831479 @default.
- W2025221802 cites W1587915607 @default.
- W2025221802 cites W1712380815 @default.
- W2025221802 cites W1836776986 @default.
- W2025221802 cites W1966718261 @default.
- W2025221802 cites W1966833359 @default.
- W2025221802 cites W1967203813 @default.
- W2025221802 cites W1969465952 @default.
- W2025221802 cites W1974688234 @default.
- W2025221802 cites W1976201852 @default.
- W2025221802 cites W1977820570 @default.
- W2025221802 cites W2002559713 @default.
- W2025221802 cites W2021785060 @default.
- W2025221802 cites W2031007679 @default.
- W2025221802 cites W2031382376 @default.
- W2025221802 cites W2036642815 @default.
- W2025221802 cites W2038673804 @default.
- W2025221802 cites W2042493764 @default.
- W2025221802 cites W2053849091 @default.
- W2025221802 cites W2058540510 @default.
- W2025221802 cites W2058669736 @default.
- W2025221802 cites W2062550706 @default.
- W2025221802 cites W2062624942 @default.
- W2025221802 cites W2063149940 @default.
- W2025221802 cites W2066933443 @default.
- W2025221802 cites W2068738612 @default.
- W2025221802 cites W2075473248 @default.
- W2025221802 cites W2079186399 @default.
- W2025221802 cites W2083807859 @default.
- W2025221802 cites W2085899859 @default.
- W2025221802 cites W2086052553 @default.
- W2025221802 cites W2097965815 @default.
- W2025221802 cites W2103114542 @default.
- W2025221802 cites W2107840202 @default.
- W2025221802 cites W2121963977 @default.
- W2025221802 cites W2123736620 @default.
- W2025221802 cites W2126316619 @default.
- W2025221802 cites W2128634581 @default.
- W2025221802 cites W2129115026 @default.
- W2025221802 cites W2129377637 @default.
- W2025221802 cites W2132215950 @default.
- W2025221802 cites W2141421676 @default.
- W2025221802 cites W2141747047 @default.
- W2025221802 cites W2142290569 @default.
- W2025221802 cites W2145546930 @default.
- W2025221802 cites W2145626269 @default.
- W2025221802 cites W2150015073 @default.
- W2025221802 cites W2152155545 @default.
- W2025221802 cites W2154782033 @default.
- W2025221802 cites W2156193029 @default.
- W2025221802 cites W2156833102 @default.
- W2025221802 cites W2158345344 @default.
- W2025221802 cites W2159813318 @default.
- W2025221802 cites W2163210644 @default.
- W2025221802 cites W2164067932 @default.
- W2025221802 cites W2165548028 @default.
- W2025221802 cites W2171132114 @default.
- W2025221802 doi "https://doi.org/10.1111/j.1462-5822.2008.01148.x" @default.
- W2025221802 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2674401" @default.
- W2025221802 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18373633" @default.
- W2025221802 hasPublicationYear "2008" @default.
- W2025221802 type Work @default.
- W2025221802 sameAs 2025221802 @default.
- W2025221802 citedByCount "64" @default.
- W2025221802 countsByYear W20252218022012 @default.
- W2025221802 countsByYear W20252218022013 @default.
- W2025221802 countsByYear W20252218022014 @default.
- W2025221802 countsByYear W20252218022015 @default.
- W2025221802 countsByYear W20252218022016 @default.
- W2025221802 countsByYear W20252218022017 @default.
- W2025221802 countsByYear W20252218022018 @default.
- W2025221802 countsByYear W20252218022019 @default.
- W2025221802 countsByYear W20252218022020 @default.
- W2025221802 countsByYear W20252218022021 @default.
- W2025221802 countsByYear W20252218022022 @default.
- W2025221802 countsByYear W20252218022023 @default.
- W2025221802 crossrefType "journal-article" @default.
- W2025221802 hasAuthorship W2025221802A5005219196 @default.
- W2025221802 hasAuthorship W2025221802A5024846442 @default.
- W2025221802 hasBestOaLocation W20252218021 @default.
- W2025221802 hasConcept C104317684 @default.
- W2025221802 hasConcept C131934819 @default.
- W2025221802 hasConcept C136238340 @default.
- W2025221802 hasConcept C142724271 @default.
- W2025221802 hasConcept C2777633098 @default.
- W2025221802 hasConcept C2779134260 @default.
- W2025221802 hasConcept C2909607560 @default.
- W2025221802 hasConcept C2994168385 @default.
- W2025221802 hasConcept C3019447875 @default.