FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2025223859> ?p ?o ?g. }

• W2025223859 endingPage "122" @default.
• W2025223859 startingPage "113" @default.
• W2025223859 abstract "High Alcohol Withdrawal (HAW) and Low Alcohol Withdrawal (LAW) mice were selectively bred from a foundation population of C57BL6/J (B6) x DBA/2J (D2) F2 intercross progeny for display of intense or mild handling-induced withdrawal convulsions, respectively, following a single injection of a hypnotic dose of ethanol (alcohol; 4 g/kg). The HAW line had significantly greater alcohol withdrawal severity scores compared to the LAW line after only a single generation of selection; the magnitude of the line difference was 8-fold by the fourth selected generation. We tested these lines for severity of withdrawal convulsions following the benzodiazepine, diazepam; the gaseous anesthetic, nitrous oxide; the imidazopyridine, zolpidem and the barbiturate, pentobarbital. In all cases, HAW mice had significantly greater withdrawal severity than mice of the LAW line. These results indicate that some genes influencing withdrawal convulsion severity following ethanol also affect withdrawal from other CNS depressants. D2 mice are more sensitive to a variety of convulsants than B6 mice (and have more severe withdrawal convulsions). We, therefore, tested separate groups of mice of both selectively bred lines for threshold sensitivity to pentylenetetrazol (PTZ), N-methyl-D-aspartate (NMDA) and kainic acid (KA). No line differences were detected. These results indicate that genes influencing severity of withdrawal from several depressant drugs are largely different from those affecting susceptibility to GABAergic or glutamatergic convulsants." @default.
• W2025223859 created "2016-06-24" @default.
• W2025223859 creator A5038492593 @default.
• W2025223859 creator A5053304883 @default.
• W2025223859 creator A5084447586 @default.
• W2025223859 date "1998-09-01" @default.
• W2025223859 modified "2023-09-27" @default.
• W2025223859 title "Drug withdrawal convulsions and susceptibility to convulsants after short-term selective breeding for acute ethanol withdrawal" @default.
• W2025223859 cites W109192066 @default.
• W2025223859 cites W1487305712 @default.
• W2025223859 cites W1937687163 @default.
• W2025223859 cites W1965202103 @default.
• W2025223859 cites W1969683921 @default.
• W2025223859 cites W1971296295 @default.
• W2025223859 cites W1985105050 @default.
• W2025223859 cites W1986214751 @default.
• W2025223859 cites W1994534741 @default.
• W2025223859 cites W2002049714 @default.
• W2025223859 cites W2002353847 @default.
• W2025223859 cites W2008094748 @default.
• W2025223859 cites W2010120512 @default.
• W2025223859 cites W2015244366 @default.
• W2025223859 cites W2031079587 @default.
• W2025223859 cites W2063618253 @default.
• W2025223859 cites W2072257351 @default.
• W2025223859 cites W2073081959 @default.
• W2025223859 cites W2077442784 @default.
• W2025223859 cites W2078146305 @default.
• W2025223859 cites W2079214445 @default.
• W2025223859 cites W2081081016 @default.
• W2025223859 cites W2081336349 @default.
• W2025223859 cites W2085880679 @default.
• W2025223859 cites W2106001183 @default.
• W2025223859 cites W2150988578 @default.
• W2025223859 cites W2412708681 @default.
• W2025223859 doi "https://doi.org/10.1016/s0166-4328(97)00216-7" @default.
• W2025223859 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9754883" @default.
• W2025223859 hasPublicationYear "1998" @default.
• W2025223859 type Work @default.
• W2025223859 sameAs 2025223859 @default.
• W2025223859 citedByCount "36" @default.
• W2025223859 countsByYear W20252238592013 @default.
• W2025223859 countsByYear W20252238592014 @default.
• W2025223859 countsByYear W20252238592016 @default.
• W2025223859 countsByYear W20252238592017 @default.
• W2025223859 countsByYear W20252238592018 @default.
• W2025223859 countsByYear W20252238592020 @default.
• W2025223859 crossrefType "journal-article" @default.
• W2025223859 hasAuthorship W2025223859A5038492593 @default.
• W2025223859 hasAuthorship W2025223859A5053304883 @default.
• W2025223859 hasAuthorship W2025223859A5084447586 @default.
• W2025223859 hasConcept C100691959 @default.
• W2025223859 hasConcept C118552586 @default.
• W2025223859 hasConcept C126322002 @default.
• W2025223859 hasConcept C170493617 @default.
• W2025223859 hasConcept C185592680 @default.
• W2025223859 hasConcept C2775858608 @default.
• W2025223859 hasConcept C2776175493 @default.
• W2025223859 hasConcept C2776755955 @default.
• W2025223859 hasConcept C2776819090 @default.
• W2025223859 hasConcept C2777010014 @default.
• W2025223859 hasConcept C2778173252 @default.
• W2025223859 hasConcept C2778186239 @default.
• W2025223859 hasConcept C2780077838 @default.
• W2025223859 hasConcept C2780161600 @default.
• W2025223859 hasConcept C2780376393 @default.
• W2025223859 hasConcept C2780930544 @default.
• W2025223859 hasConcept C2908647359 @default.
• W2025223859 hasConcept C2908958330 @default.
• W2025223859 hasConcept C42219234 @default.
• W2025223859 hasConcept C55493867 @default.
• W2025223859 hasConcept C71924100 @default.
• W2025223859 hasConcept C98274493 @default.
• W2025223859 hasConcept C99454951 @default.
• W2025223859 hasConceptScore W2025223859C100691959 @default.
• W2025223859 hasConceptScore W2025223859C118552586 @default.
• W2025223859 hasConceptScore W2025223859C126322002 @default.
• W2025223859 hasConceptScore W2025223859C170493617 @default.
• W2025223859 hasConceptScore W2025223859C185592680 @default.
• W2025223859 hasConceptScore W2025223859C2775858608 @default.
• W2025223859 hasConceptScore W2025223859C2776175493 @default.
• W2025223859 hasConceptScore W2025223859C2776755955 @default.
• W2025223859 hasConceptScore W2025223859C2776819090 @default.
• W2025223859 hasConceptScore W2025223859C2777010014 @default.
• W2025223859 hasConceptScore W2025223859C2778173252 @default.
• W2025223859 hasConceptScore W2025223859C2778186239 @default.
• W2025223859 hasConceptScore W2025223859C2780077838 @default.
• W2025223859 hasConceptScore W2025223859C2780161600 @default.
• W2025223859 hasConceptScore W2025223859C2780376393 @default.
• W2025223859 hasConceptScore W2025223859C2780930544 @default.
• W2025223859 hasConceptScore W2025223859C2908647359 @default.
• W2025223859 hasConceptScore W2025223859C2908958330 @default.
• W2025223859 hasConceptScore W2025223859C42219234 @default.
• W2025223859 hasConceptScore W2025223859C55493867 @default.
• W2025223859 hasConceptScore W2025223859C71924100 @default.
• W2025223859 hasConceptScore W2025223859C98274493 @default.
• W2025223859 hasConceptScore W2025223859C99454951 @default.
• W2025223859 hasIssue "1" @default.

• next