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- W2025243388 abstract "We investigated whether cellular responses to various stress conditions are regulated in synchronization with the ultradian rhythm of respiratory-fermentative metabolism which is coupled to the cell cycle rhythm in continuous cultures of the yeast Saccharomyces cerevisiae. The cellular resistance to heat oscillated with a peak at the late respiro-fermentative phase, which approximately corresponds to the unbudding period of the cell cycle. Cellular resistance to H(2)O(2) and that to the superoxide-generating agent menadione oscillated in the same phase as that of heat resistance. The resistance to cadmium and that to 1-chloro-2,4-dinitrobenzene, an uncoupler of energy metabolism in mitochondria, both oscillated with a peak advanced by about 80 degrees relative to that of heat resistance, approximately covering the respiro-fermentative phase. Thus, cellular resistance to various stresses in S. cerevisiae oscillated in synchronization with the metabolic oscillation in the continuous culture." @default.
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- W2025243388 date "2000-08-01" @default.
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- W2025243388 title "Cellular stress responses oscillate in synchronization with the ultradian oscillation of energy metabolism in the yeast<i>Saccharomyces cerevisiae</i>" @default.
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- W2025243388 doi "https://doi.org/10.1111/j.1574-6968.2000.tb09198.x" @default.
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