Matches in SemOpenAlex for { <https://semopenalex.org/work/W2025252954> ?p ?o ?g. }
- W2025252954 endingPage "421" @default.
- W2025252954 startingPage "409" @default.
- W2025252954 abstract "To investigate the influence of the ribosomal DNA enhancer on initiation of replication and recombination at the ribosomal array, we used yeast S. cerevisiae strains with adjacent, tagged rRNA genes. We found that the enhancer is an absolute requirement for replication fork barrier function, while it only modulates initiation of replication. Moreover, the formation of monomeric extrachromosomal ribosomal circles depends on this element. Our data indicate that DNA double-strand breaks occur at specific sites in the parental leading arm of replication forks stalled at the replication fork barrier. Additionally, nicks upstream of the replication fork barrier were visualized by nucleotide-resolution mapping. They coincide with essential sequences of the mitotic hyperrecombination site HOT1, which previously has been determined at ectopic sites. Interestingly, these nicks are strictly dependent on the replication fork blocking-protein (Fob1), but are replication independent, suggesting that intrachromosomal ribosomal DNA recombination may occur outside of S phase." @default.
- W2025252954 created "2016-06-24" @default.
- W2025252954 creator A5001373766 @default.
- W2025252954 creator A5010905874 @default.
- W2025252954 date "2004-08-01" @default.
- W2025252954 modified "2023-09-24" @default.
- W2025252954 title "rDNA Enhancer Affects Replication Initiation and Mitotic Recombination" @default.
- W2025252954 cites W1559338898 @default.
- W2025252954 cites W1887868672 @default.
- W2025252954 cites W1963578989 @default.
- W2025252954 cites W1964699435 @default.
- W2025252954 cites W1968917541 @default.
- W2025252954 cites W1972750899 @default.
- W2025252954 cites W1975817822 @default.
- W2025252954 cites W1977839031 @default.
- W2025252954 cites W1978680674 @default.
- W2025252954 cites W1982166181 @default.
- W2025252954 cites W1995753204 @default.
- W2025252954 cites W2001005729 @default.
- W2025252954 cites W2003766273 @default.
- W2025252954 cites W2010292457 @default.
- W2025252954 cites W2018502015 @default.
- W2025252954 cites W2022166341 @default.
- W2025252954 cites W2024194876 @default.
- W2025252954 cites W2039828196 @default.
- W2025252954 cites W2053259460 @default.
- W2025252954 cites W2059185956 @default.
- W2025252954 cites W2071816222 @default.
- W2025252954 cites W2072113865 @default.
- W2025252954 cites W2092772927 @default.
- W2025252954 cites W2101330941 @default.
- W2025252954 cites W2108930841 @default.
- W2025252954 cites W2115239086 @default.
- W2025252954 cites W2116011960 @default.
- W2025252954 cites W2119748737 @default.
- W2025252954 cites W2121258571 @default.
- W2025252954 cites W2124624490 @default.
- W2025252954 cites W2127229045 @default.
- W2025252954 cites W2131674896 @default.
- W2025252954 cites W2134485635 @default.
- W2025252954 cites W2141642740 @default.
- W2025252954 cites W2147791743 @default.
- W2025252954 cites W2160781488 @default.
- W2025252954 cites W2172063118 @default.
- W2025252954 cites W2284205568 @default.
- W2025252954 cites W914334466 @default.
- W2025252954 doi "https://doi.org/10.1016/j.molcel.2004.06.024" @default.
- W2025252954 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15304221" @default.
- W2025252954 hasPublicationYear "2004" @default.
- W2025252954 type Work @default.
- W2025252954 sameAs 2025252954 @default.
- W2025252954 citedByCount "82" @default.
- W2025252954 countsByYear W20252529542012 @default.
- W2025252954 countsByYear W20252529542013 @default.
- W2025252954 countsByYear W20252529542014 @default.
- W2025252954 countsByYear W20252529542015 @default.
- W2025252954 countsByYear W20252529542016 @default.
- W2025252954 countsByYear W20252529542017 @default.
- W2025252954 countsByYear W20252529542018 @default.
- W2025252954 countsByYear W20252529542019 @default.
- W2025252954 countsByYear W20252529542020 @default.
- W2025252954 countsByYear W20252529542021 @default.
- W2025252954 countsByYear W20252529542022 @default.
- W2025252954 countsByYear W20252529542023 @default.
- W2025252954 crossrefType "journal-article" @default.
- W2025252954 hasAuthorship W2025252954A5001373766 @default.
- W2025252954 hasAuthorship W2025252954A5010905874 @default.
- W2025252954 hasBestOaLocation W20252529541 @default.
- W2025252954 hasConcept C104317684 @default.
- W2025252954 hasConcept C104690221 @default.
- W2025252954 hasConcept C151158763 @default.
- W2025252954 hasConcept C175248279 @default.
- W2025252954 hasConcept C188036394 @default.
- W2025252954 hasConcept C207812311 @default.
- W2025252954 hasConcept C22744801 @default.
- W2025252954 hasConcept C22840021 @default.
- W2025252954 hasConcept C41141232 @default.
- W2025252954 hasConcept C54266558 @default.
- W2025252954 hasConcept C54355233 @default.
- W2025252954 hasConcept C552990157 @default.
- W2025252954 hasConcept C58337764 @default.
- W2025252954 hasConcept C73573662 @default.
- W2025252954 hasConcept C86803240 @default.
- W2025252954 hasConcept C89684784 @default.
- W2025252954 hasConcept C90132467 @default.
- W2025252954 hasConcept C95444343 @default.
- W2025252954 hasConcept C98086919 @default.
- W2025252954 hasConceptScore W2025252954C104317684 @default.
- W2025252954 hasConceptScore W2025252954C104690221 @default.
- W2025252954 hasConceptScore W2025252954C151158763 @default.
- W2025252954 hasConceptScore W2025252954C175248279 @default.
- W2025252954 hasConceptScore W2025252954C188036394 @default.
- W2025252954 hasConceptScore W2025252954C207812311 @default.
- W2025252954 hasConceptScore W2025252954C22744801 @default.
- W2025252954 hasConceptScore W2025252954C22840021 @default.
- W2025252954 hasConceptScore W2025252954C41141232 @default.
- W2025252954 hasConceptScore W2025252954C54266558 @default.
- W2025252954 hasConceptScore W2025252954C54355233 @default.