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• W2025257380 abstract "Aza TSAO-T derivatives bearing a dihydroisothiazole dioxide ring instead of an oxathiole dioxide ring at the C-3' position on the sugar moiety were prepared. We have synthesized four families of compounds depending on substitution at both N-3 and N-2' '. Biological evaluation showed that these compounds are HIV-1(III(B))-specific and potent reverse transcriptase inhibitors with EC(50) values between 0.13 and 3.5 microM in cell culture." @default.
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• W2025257380 date "2005-05-26" @default.
• W2025257380 modified "2023-10-04" @default.
• W2025257380 title "First Synthesis and Evaluation of the Inhibitory Effects of Aza Analogues of TSAO on HIV-1 Replication" @default.
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• W2025257380 doi "https://doi.org/10.1021/jm050091g" @default.
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