FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2025289882> ?p ?o ?g. }

• W2025289882 endingPage "e83255" @default.
• W2025289882 startingPage "e83255" @default.
• W2025289882 abstract "Background Impairments in mismatch negativity (MMN) generation have been consistently reported in patients with schizophrenia. However, underlying oscillatory activity of MMN deficits in schizophrenia and the relationship with cognitive impairments have not been investigated in detail. Time-frequency power and phase analyses can provide more detailed measures of brain dynamics of MMN deficits in schizophrenia. Method 21 patients with schizophrenia and 21 healthy controls were tested with a roving frequency paradigm to generate MMN. Time-frequency domain power and phase-locking (PL) analysis was performed on all trials using short-time Fourier transforms with Hanning window tapering. A comprehensive battery (CANTAB) was used to assess neurocognitive functioning. Results Mean MMN amplitude was significantly lower in patients with schizophrenia (95% CI 0.18 - 0.77). Patients showed significantly lower EEG power (95% CI -1.02 - -0.014) in the ~4-7 Hz frequency range (theta band) between 170 and 210 ms. Patients with schizophrenia showed cognitive impairment in multiple domains of CANTAB. However, MMN impairments in amplitude and power were not correlated with clinical measures, medication dose, social functioning or neurocognitive performance. Conclusion The findings from this study suggested that while MMN may be a useful marker to probe NMDA receptor mediated mechanisms and associated impairments in gain control and perceptual changes, it may not be a useful marker in association with clinical or cognitive changes. Trial-by-trial EEG power analysis can be used as a measure of brain dynamics underlying MMN deficits which also can have implications for the use of MMN as a biomarker for drug discovery." @default.
• W2025289882 created "2016-06-24" @default.
• W2025289882 creator A5001897074 @default.
• W2025289882 creator A5008204996 @default.
• W2025289882 creator A5009709167 @default.
• W2025289882 creator A5014148557 @default.
• W2025289882 creator A5018958936 @default.
• W2025289882 creator A5022265004 @default.
• W2025289882 creator A5027917089 @default.
• W2025289882 creator A5031004865 @default.
• W2025289882 creator A5032516527 @default.
• W2025289882 creator A5041538919 @default.
• W2025289882 creator A5060510561 @default.
• W2025289882 creator A5062030315 @default.
• W2025289882 creator A5076646790 @default.
• W2025289882 date "2013-12-17" @default.
• W2025289882 modified "2023-10-18" @default.
• W2025289882 title "Oscillatory Underpinnings of Mismatch Negativity and Their Relationship with Cognitive Function in Patients with Schizophrenia" @default.
• W2025289882 cites W1760918140 @default.
• W2025289882 cites W1966108468 @default.
• W2025289882 cites W1971109120 @default.
• W2025289882 cites W1976676889 @default.
• W2025289882 cites W1978322265 @default.
• W2025289882 cites W1978538293 @default.
• W2025289882 cites W1982173910 @default.
• W2025289882 cites W1989324273 @default.
• W2025289882 cites W1991664166 @default.
• W2025289882 cites W1993727269 @default.
• W2025289882 cites W1996141026 @default.
• W2025289882 cites W2005125144 @default.
• W2025289882 cites W2008448232 @default.
• W2025289882 cites W2008639041 @default.
• W2025289882 cites W2011311380 @default.
• W2025289882 cites W2015919911 @default.
• W2025289882 cites W2016391660 @default.
• W2025289882 cites W2019103388 @default.
• W2025289882 cites W2028884770 @default.
• W2025289882 cites W2029057559 @default.
• W2025289882 cites W2033538767 @default.
• W2025289882 cites W2036007897 @default.
• W2025289882 cites W2039463270 @default.
• W2025289882 cites W2042338392 @default.
• W2025289882 cites W2049328501 @default.
• W2025289882 cites W2050566450 @default.
• W2025289882 cites W2051612813 @default.
• W2025289882 cites W2057964653 @default.
• W2025289882 cites W2063637332 @default.
• W2025289882 cites W2072438822 @default.
• W2025289882 cites W2075307384 @default.
• W2025289882 cites W2075524608 @default.
• W2025289882 cites W2082144190 @default.
• W2025289882 cites W2082297964 @default.
• W2025289882 cites W2096230543 @default.
• W2025289882 cites W2100741386 @default.
• W2025289882 cites W2104619913 @default.
• W2025289882 cites W2105732570 @default.
• W2025289882 cites W2107094155 @default.
• W2025289882 cites W2107549990 @default.
• W2025289882 cites W2117037255 @default.
• W2025289882 cites W2125206183 @default.
• W2025289882 cites W2125315608 @default.
• W2025289882 cites W2127958135 @default.
• W2025289882 cites W2128495200 @default.
• W2025289882 cites W2128872279 @default.
• W2025289882 cites W2134423345 @default.
• W2025289882 cites W2135278585 @default.
• W2025289882 cites W2136729540 @default.
• W2025289882 cites W2138815477 @default.
• W2025289882 cites W2139196515 @default.
• W2025289882 cites W2140606211 @default.
• W2025289882 cites W2142009972 @default.
• W2025289882 cites W2142875089 @default.
• W2025289882 cites W2155988173 @default.
• W2025289882 cites W2156520006 @default.
• W2025289882 cites W2161401886 @default.
• W2025289882 cites W2163465422 @default.
• W2025289882 cites W2165647449 @default.
• W2025289882 cites W2167579305 @default.
• W2025289882 cites W2169619011 @default.
• W2025289882 cites W2169756567 @default.
• W2025289882 cites W2170792659 @default.
• W2025289882 cites W66916260 @default.
• W2025289882 doi "https://doi.org/10.1371/journal.pone.0083255" @default.
• W2025289882 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3866183" @default.
• W2025289882 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24358266" @default.
• W2025289882 hasPublicationYear "2013" @default.
• W2025289882 type Work @default.
• W2025289882 sameAs 2025289882 @default.
• W2025289882 citedByCount "34" @default.
• W2025289882 countsByYear W20252898822014 @default.
• W2025289882 countsByYear W20252898822015 @default.
• W2025289882 countsByYear W20252898822016 @default.
• W2025289882 countsByYear W20252898822017 @default.
• W2025289882 countsByYear W20252898822018 @default.
• W2025289882 countsByYear W20252898822019 @default.
• W2025289882 countsByYear W20252898822020 @default.
• W2025289882 countsByYear W20252898822021 @default.
• W2025289882 countsByYear W20252898822022 @default.

• next