Matches in SemOpenAlex for { <https://semopenalex.org/work/W2025310411> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W2025310411 endingPage "484" @default.
- W2025310411 startingPage "478" @default.
- W2025310411 abstract "Excess surfactant present in emulsions can influence the rates of transport of incorporated drugs by micellar solubilization, alteration of the partitioning process and by drug-surfactant complexation. Cetyltrimethylammonium bromide (CTAB), a cationic surfactant was selected to investigate these phenomena as it forms relatively stable mineral oil-water (O-W) emulsions and has the potential for ionic interaction. Phenylazoaniline, benzocaine, benzoic acid and phenol were chosen as model drugs for this study. The emulsion critical micelle concentration (CMC) for CTAB determined using a combination of a membrane equilibrium technique and surface-tension measurement was 1.0% w/v in 10% v/v% O-W emulsion systems. Ionic interaction between model drugs and surfactants and drug hydrophobicity affected their transport rates in the emulsion systems. The transport rates of the lipophilic drugs (benzocaine and phenylazoaniline) and the ionized hydrophillic drug (benzoic acid, pH 7.0) in the emulsion systems increased with increasing CTAB concentration up to 0.5% w/v micellar concentration and then decreased at higher concentrations. The rate of transport of phenol was not affected by the presence of micellar phase. Ionic interaction between surfactant and model drugs affected transport rates of model drugs in emulsion systems. The micellar phase was considered to affect the overall transport rates of model drugs." @default.
- W2025310411 created "2016-06-24" @default.
- W2025310411 creator A5032860462 @default.
- W2025310411 creator A5089510416 @default.
- W2025310411 date "1997-05-01" @default.
- W2025310411 modified "2023-10-16" @default.
- W2025310411 title "Effect of Cationic Surfactant on Transport of Model Drugs in Emulsion Systems" @default.
- W2025310411 cites W1527614206 @default.
- W2025310411 cites W1977353493 @default.
- W2025310411 cites W1983555315 @default.
- W2025310411 cites W1983744976 @default.
- W2025310411 cites W2014467650 @default.
- W2025310411 cites W2030527695 @default.
- W2025310411 cites W2031569105 @default.
- W2025310411 cites W2063287827 @default.
- W2025310411 cites W2076201752 @default.
- W2025310411 doi "https://doi.org/10.1111/j.2042-7158.1997.tb06827.x" @default.
- W2025310411 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9178180" @default.
- W2025310411 hasPublicationYear "1997" @default.
- W2025310411 type Work @default.
- W2025310411 sameAs 2025310411 @default.
- W2025310411 citedByCount "22" @default.
- W2025310411 countsByYear W20253104112012 @default.
- W2025310411 countsByYear W20253104112013 @default.
- W2025310411 countsByYear W20253104112016 @default.
- W2025310411 countsByYear W20253104112018 @default.
- W2025310411 crossrefType "journal-article" @default.
- W2025310411 hasAuthorship W2025310411A5032860462 @default.
- W2025310411 hasAuthorship W2025310411A5089510416 @default.
- W2025310411 hasBestOaLocation W20253104111 @default.
- W2025310411 hasConcept C11268172 @default.
- W2025310411 hasConcept C121332964 @default.
- W2025310411 hasConcept C145148216 @default.
- W2025310411 hasConcept C178790620 @default.
- W2025310411 hasConcept C179104552 @default.
- W2025310411 hasConcept C183882617 @default.
- W2025310411 hasConcept C184651966 @default.
- W2025310411 hasConcept C185592680 @default.
- W2025310411 hasConcept C190119865 @default.
- W2025310411 hasConcept C203014093 @default.
- W2025310411 hasConcept C2182769 @default.
- W2025310411 hasConcept C2776300020 @default.
- W2025310411 hasConcept C2777702071 @default.
- W2025310411 hasConcept C2778123984 @default.
- W2025310411 hasConcept C2778844314 @default.
- W2025310411 hasConcept C2779716929 @default.
- W2025310411 hasConcept C2780235077 @default.
- W2025310411 hasConcept C43617362 @default.
- W2025310411 hasConcept C55493867 @default.
- W2025310411 hasConcept C58226133 @default.
- W2025310411 hasConcept C62520636 @default.
- W2025310411 hasConcept C64237528 @default.
- W2025310411 hasConcept C86803240 @default.
- W2025310411 hasConcept C8892853 @default.
- W2025310411 hasConceptScore W2025310411C11268172 @default.
- W2025310411 hasConceptScore W2025310411C121332964 @default.
- W2025310411 hasConceptScore W2025310411C145148216 @default.
- W2025310411 hasConceptScore W2025310411C178790620 @default.
- W2025310411 hasConceptScore W2025310411C179104552 @default.
- W2025310411 hasConceptScore W2025310411C183882617 @default.
- W2025310411 hasConceptScore W2025310411C184651966 @default.
- W2025310411 hasConceptScore W2025310411C185592680 @default.
- W2025310411 hasConceptScore W2025310411C190119865 @default.
- W2025310411 hasConceptScore W2025310411C203014093 @default.
- W2025310411 hasConceptScore W2025310411C2182769 @default.
- W2025310411 hasConceptScore W2025310411C2776300020 @default.
- W2025310411 hasConceptScore W2025310411C2777702071 @default.
- W2025310411 hasConceptScore W2025310411C2778123984 @default.
- W2025310411 hasConceptScore W2025310411C2778844314 @default.
- W2025310411 hasConceptScore W2025310411C2779716929 @default.
- W2025310411 hasConceptScore W2025310411C2780235077 @default.
- W2025310411 hasConceptScore W2025310411C43617362 @default.
- W2025310411 hasConceptScore W2025310411C55493867 @default.
- W2025310411 hasConceptScore W2025310411C58226133 @default.
- W2025310411 hasConceptScore W2025310411C62520636 @default.
- W2025310411 hasConceptScore W2025310411C64237528 @default.
- W2025310411 hasConceptScore W2025310411C86803240 @default.
- W2025310411 hasConceptScore W2025310411C8892853 @default.
- W2025310411 hasIssue "5" @default.
- W2025310411 hasLocation W20253104111 @default.
- W2025310411 hasLocation W20253104112 @default.
- W2025310411 hasOpenAccess W2025310411 @default.
- W2025310411 hasPrimaryLocation W20253104111 @default.
- W2025310411 hasRelatedWork W1138749031 @default.
- W2025310411 hasRelatedWork W1986542906 @default.
- W2025310411 hasRelatedWork W1996343328 @default.
- W2025310411 hasRelatedWork W2069143573 @default.
- W2025310411 hasRelatedWork W2072305804 @default.
- W2025310411 hasRelatedWork W2078631977 @default.
- W2025310411 hasRelatedWork W2418163144 @default.
- W2025310411 hasRelatedWork W2551946382 @default.
- W2025310411 hasRelatedWork W2894898143 @default.
- W2025310411 hasRelatedWork W617506740 @default.
- W2025310411 hasVolume "49" @default.
- W2025310411 isParatext "false" @default.
- W2025310411 isRetracted "false" @default.
- W2025310411 magId "2025310411" @default.
- W2025310411 workType "article" @default.