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- W2025319797 abstract "Publisher Summary This chapter focuses on the phagotrophy and pigment formation in a chloroquine-resistant strain of Plasmodium berghei. The morphology of parasites from a normal but non gametocyte-producing strain (N) and a chloroquine resistant strain (RC) of P.berghei was compared by the means of normal or phase-contrast light microscopy and the electron microscope. For the latter purpose whole blood, clotted, fixed firstly in glutaraldehyde and later in osmic acid, embedded in Araldite and stained both with uranyl acetate and lead hydroxide, proved the most satisfactory. Parasites of both strains are seen to feed by phagotrophy. While normal parasites usually have only one large food vacuole, RC parasites may have up to about six smaller vacuoles simultaneously. These give the parasites a foamy appearance by light microscopy. The granules of pigment, hemozoin, that are typical in the genus Plasmodium and are clearly seen in N strain trophozoites and schizonts, are absent from these stages of the RC strain. Minute particles in the cytoplasm of the latter may represent the last remnants of digested erythrocyte stroma." @default.
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- W2025319797 date "1966-01-01" @default.
- W2025319797 modified "2023-09-28" @default.
- W2025319797 title "PHAGOTROPHY AND PIGMENT FORMATION IN A CHLOROQUINE-RESISTANT STRAIN OF PLASMODIUM BERGHEI" @default.
- W2025319797 doi "https://doi.org/10.1016/b978-1-4832-2913-3.50209-4" @default.
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