FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2025393438> ?p ?o ?g. }

• W2025393438 endingPage "10" @default.
• W2025393438 startingPage "1" @default.
• W2025393438 abstract "Leu162Val PPAR α and Pro12Ala PPAR γ 2 were investigated for their individual and their interactive impact on MS and renal functionality (RF). 522 subjects were investigated for biochemical and anthropometric measurements. The diagnosis of MS was based on the IDF definition (2009). The HOMA 2 was used to determine HOMA- β , HOMA-S and HOMA-IR from FPG and FPI concentrations. RF was assessed by estimating the GFR. PCR-RFLP was performed for DNA genotyping. Allele frequencies were 0.845 for Pro and 0.155 for Ala, and were 0.915 for Leu and 0.085 for Val. We showed that carriers of the PPAR α Val 162 allele had lower urea, UA and higher GFR compared to those homozygous for the Leu162 allele. Subjects carried by PPAR γ 2Ala allele had similar results. They also had reduced FPG, FPI and HOMA-IR, and elevated HOMA- β and HOMA-S compared to those homozygous for the Pro allele. Subjects were divided into 4 groups according to the combinations of genetic alleles of the 2 polymorphisms. Subjects carrying the Leu/Val with an Ala allele had lower FPG, PPI, HOMA-IR, urea, UA levels, higher HOMA- β , HOMA-S and GFR than different genotype combinations. Leu162Val PPAR α and Pro12Ala PPAR γ 2 can interact with each other to modulate glucose and insulin homeostasis and expand their association with overall better RF." @default.
• W2025393438 created "2016-06-24" @default.
• W2025393438 creator A5007839725 @default.
• W2025393438 creator A5022229139 @default.
• W2025393438 creator A5035532926 @default.
• W2025393438 creator A5055494902 @default.
• W2025393438 creator A5060150664 @default.
• W2025393438 creator A5068322635 @default.
• W2025393438 creator A5072496586 @default.
• W2025393438 date "2013-01-01" @default.
• W2025393438 modified "2023-10-17" @default.
• W2025393438 title "Interaction Effects of the Leu162Val PPARαand Pro12Ala PPARγ2 Gene Variants with Renal Function in Metabolic Syndrome Population" @default.
• W2025393438 cites W1527649416 @default.
• W2025393438 cites W1550111394 @default.
• W2025393438 cites W1812285428 @default.
• W2025393438 cites W1961916049 @default.
• W2025393438 cites W1963713924 @default.
• W2025393438 cites W1965383347 @default.
• W2025393438 cites W1977005467 @default.
• W2025393438 cites W1980374665 @default.
• W2025393438 cites W1983899279 @default.
• W2025393438 cites W1990845094 @default.
• W2025393438 cites W1995571605 @default.
• W2025393438 cites W1996256476 @default.
• W2025393438 cites W2003960793 @default.
• W2025393438 cites W2016366089 @default.
• W2025393438 cites W2017442168 @default.
• W2025393438 cites W2030180224 @default.
• W2025393438 cites W2034355953 @default.
• W2025393438 cites W2046009966 @default.
• W2025393438 cites W2052658828 @default.
• W2025393438 cites W2060678630 @default.
• W2025393438 cites W2060925587 @default.
• W2025393438 cites W2078205913 @default.
• W2025393438 cites W2094404475 @default.
• W2025393438 cites W2103213296 @default.
• W2025393438 cites W2107159320 @default.
• W2025393438 cites W2107279414 @default.
• W2025393438 cites W2108235121 @default.
• W2025393438 cites W2108702111 @default.
• W2025393438 cites W2111223640 @default.
• W2025393438 cites W2113328569 @default.
• W2025393438 cites W2115520841 @default.
• W2025393438 cites W2124620553 @default.
• W2025393438 cites W2131752045 @default.
• W2025393438 cites W2136898798 @default.
• W2025393438 cites W2143104968 @default.
• W2025393438 cites W2144055106 @default.
• W2025393438 cites W2150827260 @default.
• W2025393438 cites W2158609897 @default.
• W2025393438 cites W2161477191 @default.
• W2025393438 cites W2182504452 @default.
• W2025393438 doi "https://doi.org/10.1155/2013/329862" @default.
• W2025393438 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3649708" @default.
• W2025393438 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23690758" @default.
• W2025393438 hasPublicationYear "2013" @default.
• W2025393438 type Work @default.
• W2025393438 sameAs 2025393438 @default.
• W2025393438 citedByCount "4" @default.
• W2025393438 countsByYear W20253934382014 @default.
• W2025393438 countsByYear W20253934382017 @default.
• W2025393438 countsByYear W20253934382021 @default.
• W2025393438 crossrefType "journal-article" @default.
• W2025393438 hasAuthorship W2025393438A5007839725 @default.
• W2025393438 hasAuthorship W2025393438A5022229139 @default.
• W2025393438 hasAuthorship W2025393438A5035532926 @default.
• W2025393438 hasAuthorship W2025393438A5055494902 @default.
• W2025393438 hasAuthorship W2025393438A5060150664 @default.
• W2025393438 hasAuthorship W2025393438A5068322635 @default.
• W2025393438 hasAuthorship W2025393438A5072496586 @default.
• W2025393438 hasBestOaLocation W20253934381 @default.
• W2025393438 hasConcept C104317684 @default.
• W2025393438 hasConcept C126322002 @default.
• W2025393438 hasConcept C134018914 @default.
• W2025393438 hasConcept C135763542 @default.
• W2025393438 hasConcept C159641895 @default.
• W2025393438 hasConcept C170493617 @default.
• W2025393438 hasConcept C180754005 @default.
• W2025393438 hasConcept C187345961 @default.
• W2025393438 hasConcept C2777391703 @default.
• W2025393438 hasConcept C2779306644 @default.
• W2025393438 hasConcept C2780578515 @default.
• W2025393438 hasConcept C2908647359 @default.
• W2025393438 hasConcept C31467283 @default.
• W2025393438 hasConcept C37463918 @default.
• W2025393438 hasConcept C511355011 @default.
• W2025393438 hasConcept C54355233 @default.
• W2025393438 hasConcept C71924100 @default.
• W2025393438 hasConcept C86803240 @default.
• W2025393438 hasConcept C99454951 @default.
• W2025393438 hasConceptScore W2025393438C104317684 @default.
• W2025393438 hasConceptScore W2025393438C126322002 @default.
• W2025393438 hasConceptScore W2025393438C134018914 @default.
• W2025393438 hasConceptScore W2025393438C135763542 @default.
• W2025393438 hasConceptScore W2025393438C159641895 @default.
• W2025393438 hasConceptScore W2025393438C170493617 @default.
• W2025393438 hasConceptScore W2025393438C180754005 @default.
• W2025393438 hasConceptScore W2025393438C187345961 @default.

• next