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• W2025425510 abstract "There are few reports describing young-onset amyotrophic lateral sclerosis (ALS). Age at onset is a prognostic factor in ALS, and thus it is relevant to investigate the clinical features of very young ALS patients. We describe three young-onset ALS cases and review the literature. SOD1 mutations were not identified. Our cases and 24 others from the literature indicate that young-onset ALS is characterized by slowly progressive symmetrical weakness; nevertheless, progression is variable. Young-onset ALS seems to be a distinct clinical syndrome but its aetiological background is largely unknown." @default.
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• W2025425510 date "2007-01-01" @default.
• W2025425510 modified "2023-10-14" @default.
• W2025425510 title "Young‐onset sporadic amyotrophic lateral sclerosis: A distinct nosological entity?" @default.
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• W2025425510 doi "https://doi.org/10.1080/17482960701553956" @default.
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